Integrated PPI- and WGCNA-Retrieval of Hub Gene Signatures Shared Between Barrett's Esophagus and Esophageal Adenocarcinoma

Integrated PPI- and WGCNA-Retrieval of Hub Gene Signatures Shared Between Barrett's Esophagus and Esophageal Adenocarcinoma

Esophageal adenocarcinoma (EAC) is a deadly cancer with high mortality rate, especially in economically advanced countries, while Barrett's esophagus (BE) is reported to be a precursor that strongly increases the risk of EAC. Due to the complexity of these diseases, their molecular mechanisms h...

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Bibliographic Details
Main Authors: Asma Sindhoo Nangraj, Gurudeeban Selvaraj, Satyavani Kaliamurthi, Aman Chandra Kaushik, William C. Cho, Dong Qing Wei
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-07-01
Series:Frontiers in Pharmacology
Subjects:
bioinformatics analysis
Barrett's esophagus
hub gene signature
esophageal adenocarcinoma
weighted gene co-expression network analysis
protein–protein interaction
Online Access:https://www.frontiersin.org/article/10.3389/fphar.2020.00881/full

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