Controlled Delivery of an Anti-Inflammatory Toxin to Macrophages by Mutagenesis and Nanoparticle Modification

Controlled Delivery of an Anti-Inflammatory Toxin to Macrophages by Mutagenesis and Nanoparticle Modification

Advances in drug delivery systems (DDSs) have enabled the specific delivery of drugs to target cells. Subtilase cytotoxin (SubAB) produced by certain enterohemorrhagic <i>Escherichia coli</i> strains induces endoplasmic reticulum (ER) stress and suppresses nitric oxide generation in macr...

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Bibliographic Details
Main Authors: Ayaka Harada, Hiroyasu Tsutsuki, Tianli Zhang, Kinnosuke Yahiro, Tomohiro Sawa, Takuro Niidome
Format: Article
Language:English
Published: MDPI AG 2022-06-01
Series:Nanomaterials
Subjects:
PLGA nanoparticles
anti-inflammatory
controlled drug delivery
Online Access:https://www.mdpi.com/2079-4991/12/13/2161

Internet

https://www.mdpi.com/2079-4991/12/13/2161

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