Cutaneous polyarteritis nodosa causing refractory skin deformation and pigmentation as sequel
Abstract: A 39-year-old woman presented with prominent and painful livedo reticularis lesions spreading on her upper and lower extremities. Histopathologically, the small-to medium-sized arteries in the deep dermis and subcutis showed necrotizing vasculitis with cellular infiltration, suggesting cut...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Sociedade Brasileira de Dermatologia
2017-01-01
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| Series: | Anais Brasileiros de Dermatologia |
| Subjects: | |
| Online Access: | http://www.scielo.br/pdf/abd/v92n5s1/0365-0596-abd-92-05-s1-0053.pdf |
| _version_ | 1823966182293635072 |
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| author | Karin Okada Rina Nakamori Hitoshi Mizutani Keiichi Yamanaka |
| author_facet | Karin Okada Rina Nakamori Hitoshi Mizutani Keiichi Yamanaka |
| author_sort | Karin Okada |
| collection | DOAJ |
| description | Abstract: A 39-year-old woman presented with prominent and painful livedo reticularis lesions spreading on her upper and lower extremities. Histopathologically, the small-to medium-sized arteries in the deep dermis and subcutis showed necrotizing vasculitis with cellular infiltration, suggesting cutaneous polyarteritis nodosa. The serum levels of inflammatory markers normalized with aspirin 100mg/day and prednisolone 10mg/day within 2 months, and there was no other skin or organ involvement over 18 months of follow up. However, serious refractory skin depressions and pigmentation remained after two years of treatment. This suggests the importance of early and aggressive therapy for cutaneous polyarteritis nodosa to prevent unsightly skin sequel, as well as control of disease activity. |
| first_indexed | 2024-12-17T18:08:46Z |
| format | Article |
| id | doaj.art-15bcf247316142c0a4663f1e006ee2fb |
| institution | Directory Open Access Journal |
| issn | 0365-0596 |
| language | English |
| last_indexed | 2024-12-17T18:08:46Z |
| publishDate | 2017-01-01 |
| publisher | Sociedade Brasileira de Dermatologia |
| record_format | Article |
| series | Anais Brasileiros de Dermatologia |
| spelling | doaj.art-15bcf247316142c0a4663f1e006ee2fb2022-12-21T21:38:03ZengSociedade Brasileira de DermatologiaAnais Brasileiros de Dermatologia0365-05962017-01-01925 suppl 1535510.1590/abd1806-4841.20175696Cutaneous polyarteritis nodosa causing refractory skin deformation and pigmentation as sequelKarin OkadaRina NakamoriHitoshi MizutaniKeiichi YamanakaAbstract: A 39-year-old woman presented with prominent and painful livedo reticularis lesions spreading on her upper and lower extremities. Histopathologically, the small-to medium-sized arteries in the deep dermis and subcutis showed necrotizing vasculitis with cellular infiltration, suggesting cutaneous polyarteritis nodosa. The serum levels of inflammatory markers normalized with aspirin 100mg/day and prednisolone 10mg/day within 2 months, and there was no other skin or organ involvement over 18 months of follow up. However, serious refractory skin depressions and pigmentation remained after two years of treatment. This suggests the importance of early and aggressive therapy for cutaneous polyarteritis nodosa to prevent unsightly skin sequel, as well as control of disease activity.http://www.scielo.br/pdf/abd/v92n5s1/0365-0596-abd-92-05-s1-0053.pdfPigmentationPolyarteritis nodosaVasculitis |
| spellingShingle | Karin Okada Rina Nakamori Hitoshi Mizutani Keiichi Yamanaka Cutaneous polyarteritis nodosa causing refractory skin deformation and pigmentation as sequel Anais Brasileiros de Dermatologia Pigmentation Polyarteritis nodosa Vasculitis |
| title | Cutaneous polyarteritis nodosa causing refractory skin deformation and pigmentation as sequel |
| title_full | Cutaneous polyarteritis nodosa causing refractory skin deformation and pigmentation as sequel |
| title_fullStr | Cutaneous polyarteritis nodosa causing refractory skin deformation and pigmentation as sequel |
| title_full_unstemmed | Cutaneous polyarteritis nodosa causing refractory skin deformation and pigmentation as sequel |
| title_short | Cutaneous polyarteritis nodosa causing refractory skin deformation and pigmentation as sequel |
| title_sort | cutaneous polyarteritis nodosa causing refractory skin deformation and pigmentation as sequel |
| topic | Pigmentation Polyarteritis nodosa Vasculitis |
| url | http://www.scielo.br/pdf/abd/v92n5s1/0365-0596-abd-92-05-s1-0053.pdf |
| work_keys_str_mv | AT karinokada cutaneouspolyarteritisnodosacausingrefractoryskindeformationandpigmentationassequel AT rinanakamori cutaneouspolyarteritisnodosacausingrefractoryskindeformationandpigmentationassequel AT hitoshimizutani cutaneouspolyarteritisnodosacausingrefractoryskindeformationandpigmentationassequel AT keiichiyamanaka cutaneouspolyarteritisnodosacausingrefractoryskindeformationandpigmentationassequel |