Furanocoumarin Notopterol: Inhibition of Hepatocellular Carcinogenesis through Suppression of Cancer Stemness Signaling and Induction of Oxidative Stress-Associated Cell Death

Furanocoumarin Notopterol: Inhibition of Hepatocellular Carcinogenesis through Suppression of Cancer Stemness Signaling and Induction of Oxidative Stress-Associated Cell Death

Background: Hepatocellular carcinoma (HCC) remains an aggressive malignancy with a poor prognosis and a leading cause of cancer-related mortality globally. Cumulative evidence suggests critical roles for endoplasmic reticulum (ER) stress and unfolded protein response (UPR) in chronic liver diseases....

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Bibliographic Details
Main Authors: Ting-Yun Huang, Ching-Kuo Yang, Ming-Yao Chen, Vijesh Kumar Yadav, Iat-Hang Fong, Chi-Tai Yeh, Yih-Giun Cherng
Format: Article
Language:English
Published: MDPI AG 2023-05-01
Series:Nutrients
Subjects:
hepatocellular carcinoma
HCC
notopterol
anticancer treatment
oxidative stress
endoplasmic reticulum stress
Online Access:https://www.mdpi.com/2072-6643/15/11/2447

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