Periplasmic oxidized-protein repair during copper stress in E. coli: A focus on the metallochaperone CusF.

Methionine residues are particularly sensitive to oxidation by reactive oxygen or chlorine species (ROS/RCS), leading to the appearance of methionine sulfoxide in proteins. This post-translational oxidation can be reversed by omnipresent protein repair pathways involving methionine sulfoxide reducta...

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Bibliographic Details
Main Authors: Alexandra Vergnes, Camille Henry, Gaia Grassini, Laurent Loiseau, Sara El Hajj, Yann Denis, Anne Galinier, Didier Vertommen, Laurent Aussel, Benjamin Ezraty
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2022-07-01
Series:PLoS Genetics
Online Access:https://doi.org/10.1371/journal.pgen.1010180

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