P159 CORRELATION BETWEEN INFLAMMATORY STATE AND ARTERIAL STIFFNESS
Pulse wave velocity (PWV) is gold standard for assessing arterial stiffness. Studies have shown that people with metabolic syndrome have insulin resistance and that after the onset of diabetes, cardiovascular risk is intensely increased, high-sensitive C-reactive protein (hsCRP) (1). Relate influenc...
| Main Authors: | , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
BMC
2018-12-01
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| Series: | Artery Research |
| Online Access: | https://www.atlantis-press.com/article/125930147/view |
| _version_ | 1818006385233756160 |
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| author | Daniele Brustolim Lucelia Magalhaes Diorlene Silva Rodrigo Sant’Ana de Lima Vinicius Louzada Castro Daniel Malta Ribeiro Caroline Rodrigues Fidelman Natalia Damasceno Larissa Vasconcelos Caroline Ventura Vascor Group |
| author_facet | Daniele Brustolim Lucelia Magalhaes Diorlene Silva Rodrigo Sant’Ana de Lima Vinicius Louzada Castro Daniel Malta Ribeiro Caroline Rodrigues Fidelman Natalia Damasceno Larissa Vasconcelos Caroline Ventura Vascor Group |
| author_sort | Daniele Brustolim |
| collection | DOAJ |
| description | Pulse wave velocity (PWV) is gold standard for assessing arterial stiffness. Studies have shown that people with metabolic syndrome have insulin resistance and that after the onset of diabetes, cardiovascular risk is intensely increased, high-sensitive C-reactive protein (hsCRP) (1). Relate influence of changes in pulse wave velocity in the severity of the inflammatory state (2).
Methods: A population-based cross-sectional study representative of a neighborhood of Salvador-BA, Brazil. The overall sample is randomized in adults from the assigned area, from December 2016 to May 2018 comprise 64 people. PWV was the measuring velocity between the carotid and right femoral wave. The flattening tonometer SphygmoCor® apparatus (XCEL, AtCor Medical, Australia). Blood samples were collected to biochemistry analysis, ADVIA1800® (SiemensHealthcare Japan/Canada). The committee for research FTC protocol (No1827621). Spearman’s linear correlation coefficient between the laboratory tests and adjusted PWV were stratified according to the increased risk level of adjusted PWV. STATA v.12 for data analysis. The level of statistical significance was set at 5%.
Results: Table 1 (image 1), predominance of women (72.3%), (n = 64). When compared to the group with normal pulse wave velocity, there was an increase in the parameters of the laboratory tests in the group with an increased risk of arterial stiffness (adjusted PWV ≥ 10), the correlations in this group and the PWV were positive and weak, except for the glycemia was negative, but they were not statistically significant. Already in the group with normal PWV, the correlations were positive and weak, only triglycerides presented.
Conclusion: New molecular markers is necessary for correlate low intensity inflammation and arterial stiffness. |
| first_indexed | 2024-04-14T05:00:24Z |
| format | Article |
| id | doaj.art-15c346e34025441e897a82467208553d |
| institution | Directory Open Access Journal |
| issn | 1876-4401 |
| language | English |
| last_indexed | 2024-04-14T05:00:24Z |
| publishDate | 2018-12-01 |
| publisher | BMC |
| record_format | Article |
| series | Artery Research |
| spelling | doaj.art-15c346e34025441e897a82467208553d2022-12-22T02:10:58ZengBMCArtery Research1876-44012018-12-012410.1016/j.artres.2018.10.212P159 CORRELATION BETWEEN INFLAMMATORY STATE AND ARTERIAL STIFFNESSDaniele BrustolimLucelia MagalhaesDiorlene SilvaRodrigo Sant’Ana de LimaVinicius Louzada CastroDaniel Malta RibeiroCaroline Rodrigues FidelmanNatalia DamascenoLarissa VasconcelosCaroline VenturaVascor GroupPulse wave velocity (PWV) is gold standard for assessing arterial stiffness. Studies have shown that people with metabolic syndrome have insulin resistance and that after the onset of diabetes, cardiovascular risk is intensely increased, high-sensitive C-reactive protein (hsCRP) (1). Relate influence of changes in pulse wave velocity in the severity of the inflammatory state (2). Methods: A population-based cross-sectional study representative of a neighborhood of Salvador-BA, Brazil. The overall sample is randomized in adults from the assigned area, from December 2016 to May 2018 comprise 64 people. PWV was the measuring velocity between the carotid and right femoral wave. The flattening tonometer SphygmoCor® apparatus (XCEL, AtCor Medical, Australia). Blood samples were collected to biochemistry analysis, ADVIA1800® (SiemensHealthcare Japan/Canada). The committee for research FTC protocol (No1827621). Spearman’s linear correlation coefficient between the laboratory tests and adjusted PWV were stratified according to the increased risk level of adjusted PWV. STATA v.12 for data analysis. The level of statistical significance was set at 5%. Results: Table 1 (image 1), predominance of women (72.3%), (n = 64). When compared to the group with normal pulse wave velocity, there was an increase in the parameters of the laboratory tests in the group with an increased risk of arterial stiffness (adjusted PWV ≥ 10), the correlations in this group and the PWV were positive and weak, except for the glycemia was negative, but they were not statistically significant. Already in the group with normal PWV, the correlations were positive and weak, only triglycerides presented. Conclusion: New molecular markers is necessary for correlate low intensity inflammation and arterial stiffness.https://www.atlantis-press.com/article/125930147/view |
| spellingShingle | Daniele Brustolim Lucelia Magalhaes Diorlene Silva Rodrigo Sant’Ana de Lima Vinicius Louzada Castro Daniel Malta Ribeiro Caroline Rodrigues Fidelman Natalia Damasceno Larissa Vasconcelos Caroline Ventura Vascor Group P159 CORRELATION BETWEEN INFLAMMATORY STATE AND ARTERIAL STIFFNESS Artery Research |
| title | P159 CORRELATION BETWEEN INFLAMMATORY STATE AND ARTERIAL STIFFNESS |
| title_full | P159 CORRELATION BETWEEN INFLAMMATORY STATE AND ARTERIAL STIFFNESS |
| title_fullStr | P159 CORRELATION BETWEEN INFLAMMATORY STATE AND ARTERIAL STIFFNESS |
| title_full_unstemmed | P159 CORRELATION BETWEEN INFLAMMATORY STATE AND ARTERIAL STIFFNESS |
| title_short | P159 CORRELATION BETWEEN INFLAMMATORY STATE AND ARTERIAL STIFFNESS |
| title_sort | p159 correlation between inflammatory state and arterial stiffness |
| url | https://www.atlantis-press.com/article/125930147/view |
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