Epigenetic profiling to environmental stressors in model and non-model organisms: Ecotoxicology perspective
Epigenetics, potentially heritable changes in genome function that occur without alterations to DNA sequence, is an important but understudied component of ecotoxicology studies. A wide spectrum of environmental challenge, such as temperature, stress, diet, toxic chemicals, are known to impact on ep...
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| Format: | Article |
| Language: | English |
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Korean Society of Environmental Health and Toxicology
2018-09-01
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| Series: | Environmental Health and Toxicology |
| Subjects: | |
| Online Access: | http://www.e-eht.org/upload/pdf/eht-33-3-e2018015.pdf |
| _version_ | 1819098270761222144 |
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| author | Nivedita Chatterjee Jiwan Gim Jinhee Choi |
| author_facet | Nivedita Chatterjee Jiwan Gim Jinhee Choi |
| author_sort | Nivedita Chatterjee |
| collection | DOAJ |
| description | Epigenetics, potentially heritable changes in genome function that occur without alterations to DNA sequence, is an important but understudied component of ecotoxicology studies. A wide spectrum of environmental challenge, such as temperature, stress, diet, toxic chemicals, are known to impact on epigenetic regulatory mechanisms. Although the role of epigenetic factors in certain biological processes, such as tumourigenesis, has been heavily investigated, in ecotoxicology field, epigenetics still have attracted little attention. In ecotoxicology, potential role of epigenetics in multi- and transgenerational phenomenon to environmental stressors needs to be unrevealed. Natural variation in the epigenetic profiles of species in responses to environmental stressors, nature of dose-response relationships for epigenetic effects, and how to incorporate this information into ecological risk assessment should also require attentions. In this review, we presented the available information on epigenetics in ecotoxicological context. For this, we have conducted a systemic review on epigenetic profiling in response to environmental stressors, mostly chemical exposure, in model organisms, as well as, in ecotoxicologically relevant wildlife species. |
| first_indexed | 2024-12-22T00:28:19Z |
| format | Article |
| id | doaj.art-15c9a467748b4d50959a34ffe47442dd |
| institution | Directory Open Access Journal |
| issn | 2233-6567 |
| language | English |
| last_indexed | 2024-12-22T00:28:19Z |
| publishDate | 2018-09-01 |
| publisher | Korean Society of Environmental Health and Toxicology |
| record_format | Article |
| series | Environmental Health and Toxicology |
| spelling | doaj.art-15c9a467748b4d50959a34ffe47442dd2022-12-21T18:45:00ZengKorean Society of Environmental Health and ToxicologyEnvironmental Health and Toxicology2233-65672018-09-0133310.5620/eht.e2018015816Epigenetic profiling to environmental stressors in model and non-model organisms: Ecotoxicology perspectiveNivedita ChatterjeeJiwan GimJinhee ChoiEpigenetics, potentially heritable changes in genome function that occur without alterations to DNA sequence, is an important but understudied component of ecotoxicology studies. A wide spectrum of environmental challenge, such as temperature, stress, diet, toxic chemicals, are known to impact on epigenetic regulatory mechanisms. Although the role of epigenetic factors in certain biological processes, such as tumourigenesis, has been heavily investigated, in ecotoxicology field, epigenetics still have attracted little attention. In ecotoxicology, potential role of epigenetics in multi- and transgenerational phenomenon to environmental stressors needs to be unrevealed. Natural variation in the epigenetic profiles of species in responses to environmental stressors, nature of dose-response relationships for epigenetic effects, and how to incorporate this information into ecological risk assessment should also require attentions. In this review, we presented the available information on epigenetics in ecotoxicological context. For this, we have conducted a systemic review on epigenetic profiling in response to environmental stressors, mostly chemical exposure, in model organisms, as well as, in ecotoxicologically relevant wildlife species.http://www.e-eht.org/upload/pdf/eht-33-3-e2018015.pdfepigeneticsecotoxicologytransgenerational effectenvironmental stressorswildlife species |
| spellingShingle | Nivedita Chatterjee Jiwan Gim Jinhee Choi Epigenetic profiling to environmental stressors in model and non-model organisms: Ecotoxicology perspective Environmental Health and Toxicology epigenetics ecotoxicology transgenerational effect environmental stressors wildlife species |
| title | Epigenetic profiling to environmental stressors in model and non-model organisms: Ecotoxicology perspective |
| title_full | Epigenetic profiling to environmental stressors in model and non-model organisms: Ecotoxicology perspective |
| title_fullStr | Epigenetic profiling to environmental stressors in model and non-model organisms: Ecotoxicology perspective |
| title_full_unstemmed | Epigenetic profiling to environmental stressors in model and non-model organisms: Ecotoxicology perspective |
| title_short | Epigenetic profiling to environmental stressors in model and non-model organisms: Ecotoxicology perspective |
| title_sort | epigenetic profiling to environmental stressors in model and non model organisms ecotoxicology perspective |
| topic | epigenetics ecotoxicology transgenerational effect environmental stressors wildlife species |
| url | http://www.e-eht.org/upload/pdf/eht-33-3-e2018015.pdf |
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