Role of ROS in Aβ42 Mediated Activation of Cerebral Endothelial Cells

Introduction. There is substantial evidence that the deposition of aggregated amyloid-beta peptide (Aβ) in brain parenchyma and brain vessels is the main cause of neuronal dysfunction and death in Alzheimer’s disease (AD). Aβ exhibits multiple cytotoxic effects on neurons and glial cells and causes...

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Bibliographic Details
Main Authors: Andrey Tsoy, Bauyrzhan Umbayev, Tamara Shalakhmetova, Sholpan Askarova
Format: Article
Language:English
Published: University Library System, University of Pittsburgh 2014-12-01
Series:Central Asian Journal of Global Health
Subjects:
Online Access:http://cajgh.pitt.edu/ojs/index.php/cajgh/article/view/179