Evidence for increased interferon type I activity in CD8+ T cells in giant cell arteritis patients

Evidence for increased interferon type I activity in CD8+ T cells in giant cell arteritis patients

IntroductionGiant cell arteritis (GCA) is a vasculitis of the medium- and large-sized arteries. Interferon type I (IFN-I) is increasingly recognized as a key player in autoimmune diseases and might be involved in GCA pathogenesis, however evidence is limited. IFN-I activates Janus kinase/signal tran...

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Bibliographic Details
Main Authors: Marieke van Nieuwland, Idil Esen, Rosanne D. Reitsema, Wayel H. Abdulahad, Yannick van Sleen, William F. Jiemy, Maria Sandovici, Elisabeth Brouwer, Lenny van Bon
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-06-01
Series:Frontiers in Immunology
Subjects:
interferon
giant cell arteritis
T cell
vasculitis
large vessel vasculitis
innate immunity
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1197293/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2023.1197293/full

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