EHMT2/G9a as an Epigenetic Target in Pediatric and Adult Brain Tumors

EHMT2/G9a as an Epigenetic Target in Pediatric and Adult Brain Tumors

Epigenetic mechanisms, including post-translational modifications of DNA and histones that influence chromatin structure, regulate gene expression during normal development and are also involved in carcinogenesis and cancer progression. The histone methyltransferase G9a (euchromatic histone lysine m...

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Bibliographic Details
Main Authors: Barbara Kunzler Souza, Natalia Hogetop Freire, Mariane Jaeger, Caroline Brunetto de Farias, Algemir L. Brunetto, André T. Brunetto, Rafael Roesler
Format: Article
Language:English
Published: MDPI AG 2021-10-01
Series:International Journal of Molecular Sciences
Subjects:
G9a
EHMT2
glioblastoma
medulloblastoma
epigenetics
brain tumor
Online Access:https://www.mdpi.com/1422-0067/22/20/11292

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