Intrathecal Synthesis Index of Specific Anti-Treponema IgG: a New Tool for the Diagnosis of Neurosyphilis

Intrathecal Synthesis Index of Specific Anti-Treponema IgG: a New Tool for the Diagnosis of Neurosyphilis

ABSTRACT Neurosyphilis (NS) diagnosis is challenging because clinical signs are diverse and unspecific, and a sensitive and specific laboratory test is lacking. We tested the performance of an antibody index (AI) for intrathecal synthesis of specific anti-Treponema IgG by enzyme-linked immunosorbent...

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Bibliographic Details
Main Authors: Chloé Alberto, Christine Deffert, Nathalie Lambeng, Gautier Breville, Angèle Gayet-Ageron, Patrice Lalive, Laurence Toutous Trellu, Lionel Fontao
Format: Article
Language:English
Published: American Society for Microbiology 2022-02-01
Series:Microbiology Spectrum
Subjects:
neurosyphilis
intrathecal synthesis
specific anti-treponema IgG
otosyphilis
ocular syphilis
Online Access:https://journals.asm.org/doi/10.1128/spectrum.01477-21

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