Phylogenetic analysis of a partial L1 gene from bovine papillomavirus type 1 isolated from naturally occurring papilloma cases in the northwestern region of Turkey
This study was aimed at the molecular characterisation of bovine papillomavirus type 1 (BPV-1) isolated from papilloma cases in the northwestern region of Turkey. BPV-1 is a widely occurring oncogenic virus in cattle and is associated with benign epithelial neoplasia which causes significant economi...
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| Format: | Article |
| Language: | English |
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AOSIS
2017-06-01
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| Series: | Onderstepoort Journal of Veterinary Research |
| Subjects: | |
| Online Access: | https://ojvr.org/index.php/ojvr/article/view/1450 |
| _version_ | 1818011168712687616 |
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| author | M. Ozkan Timurkan M. Eray Alcigir |
| author_facet | M. Ozkan Timurkan M. Eray Alcigir |
| author_sort | M. Ozkan Timurkan |
| collection | DOAJ |
| description | This study was aimed at the molecular characterisation of bovine papillomavirus type 1 (BPV-1) isolated from papilloma cases in the northwestern region of Turkey. BPV-1 is a widely occurring oncogenic virus in cattle and is associated with benign epithelial neoplasia which causes significant economic losses in dairy and beef cattle because of treatment costs. In this study, 29 suspected papilloma specimens were collected from cattle in northwestern Turkey. These samples underwent molecular characterisation via the polymerase chain reaction (PCR) and sequencing analysis as well as macroscopic and histopathological examination. The histopathological examinations confirmed papilloma as the main lesion type in the specimens. Of the 29 papilloma-like tissue samples that were collected, 11 (i.e. 37.93%) were detected as positive and determined as containing BPV-1 (11 of 11, 100%). Using a partial sequence for the L1 gene acquired from GenBank, phylogenetic analysis confirmed the presence of BPV-1 and revealed that the infection might have originated in cross bred domestic and imported cattle. This study provides potentially useful information on the origin and spread of this disease. Its results can potentially aid in the development of appropriate control measures and therapeutic or vaccination strategies against the BPV-1 strain of bovine papillomatosis. |
| first_indexed | 2024-04-14T06:04:21Z |
| format | Article |
| id | doaj.art-15d5a54e5c984014aa397d6ca4ef2fe9 |
| institution | Directory Open Access Journal |
| issn | 0030-2465 2219-0635 |
| language | English |
| last_indexed | 2024-04-14T06:04:21Z |
| publishDate | 2017-06-01 |
| publisher | AOSIS |
| record_format | Article |
| series | Onderstepoort Journal of Veterinary Research |
| spelling | doaj.art-15d5a54e5c984014aa397d6ca4ef2fe92022-12-22T02:08:37ZengAOSISOnderstepoort Journal of Veterinary Research0030-24652219-06352017-06-01841e1e610.4102/ojvr.v84i1.1450564Phylogenetic analysis of a partial L1 gene from bovine papillomavirus type 1 isolated from naturally occurring papilloma cases in the northwestern region of TurkeyM. Ozkan Timurkan0M. Eray Alcigir1Department of Virology, Atatürk UniversityDepartment of Pathology, Ankara UniversityThis study was aimed at the molecular characterisation of bovine papillomavirus type 1 (BPV-1) isolated from papilloma cases in the northwestern region of Turkey. BPV-1 is a widely occurring oncogenic virus in cattle and is associated with benign epithelial neoplasia which causes significant economic losses in dairy and beef cattle because of treatment costs. In this study, 29 suspected papilloma specimens were collected from cattle in northwestern Turkey. These samples underwent molecular characterisation via the polymerase chain reaction (PCR) and sequencing analysis as well as macroscopic and histopathological examination. The histopathological examinations confirmed papilloma as the main lesion type in the specimens. Of the 29 papilloma-like tissue samples that were collected, 11 (i.e. 37.93%) were detected as positive and determined as containing BPV-1 (11 of 11, 100%). Using a partial sequence for the L1 gene acquired from GenBank, phylogenetic analysis confirmed the presence of BPV-1 and revealed that the infection might have originated in cross bred domestic and imported cattle. This study provides potentially useful information on the origin and spread of this disease. Its results can potentially aid in the development of appropriate control measures and therapeutic or vaccination strategies against the BPV-1 strain of bovine papillomatosis.https://ojvr.org/index.php/ojvr/article/view/1450phylogenetic analysisbpv-1papillomaturkey |
| spellingShingle | M. Ozkan Timurkan M. Eray Alcigir Phylogenetic analysis of a partial L1 gene from bovine papillomavirus type 1 isolated from naturally occurring papilloma cases in the northwestern region of Turkey Onderstepoort Journal of Veterinary Research phylogenetic analysis bpv-1 papilloma turkey |
| title | Phylogenetic analysis of a partial L1 gene from bovine papillomavirus type 1 isolated from naturally occurring papilloma cases in the northwestern region of Turkey |
| title_full | Phylogenetic analysis of a partial L1 gene from bovine papillomavirus type 1 isolated from naturally occurring papilloma cases in the northwestern region of Turkey |
| title_fullStr | Phylogenetic analysis of a partial L1 gene from bovine papillomavirus type 1 isolated from naturally occurring papilloma cases in the northwestern region of Turkey |
| title_full_unstemmed | Phylogenetic analysis of a partial L1 gene from bovine papillomavirus type 1 isolated from naturally occurring papilloma cases in the northwestern region of Turkey |
| title_short | Phylogenetic analysis of a partial L1 gene from bovine papillomavirus type 1 isolated from naturally occurring papilloma cases in the northwestern region of Turkey |
| title_sort | phylogenetic analysis of a partial l1 gene from bovine papillomavirus type 1 isolated from naturally occurring papilloma cases in the northwestern region of turkey |
| topic | phylogenetic analysis bpv-1 papilloma turkey |
| url | https://ojvr.org/index.php/ojvr/article/view/1450 |
| work_keys_str_mv | AT mozkantimurkan phylogeneticanalysisofapartiall1genefrombovinepapillomavirustype1isolatedfromnaturallyoccurringpapillomacasesinthenorthwesternregionofturkey AT merayalcigir phylogeneticanalysisofapartiall1genefrombovinepapillomavirustype1isolatedfromnaturallyoccurringpapillomacasesinthenorthwesternregionofturkey |