Exploring the Emergence of RNA Nucleosides and Nucleotides on the Early Earth
Understanding how life began is one of the most fascinating problems to solve. By approaching this enigma from a chemistry perspective, the goal is to define what series of chemical reactions could lead to the synthesis of nucleotides, amino acids, lipids, and other cellular components from simple f...
| Main Author: | |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2018-11-01
|
| Series: | Life |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2075-1729/8/4/57 |
| _version_ | 1828390957182091264 |
|---|---|
| author | Annabelle Biscans |
| author_facet | Annabelle Biscans |
| author_sort | Annabelle Biscans |
| collection | DOAJ |
| description | Understanding how life began is one of the most fascinating problems to solve. By approaching this enigma from a chemistry perspective, the goal is to define what series of chemical reactions could lead to the synthesis of nucleotides, amino acids, lipids, and other cellular components from simple feedstocks under prebiotically plausible conditions. It is well established that evolution of life involved RNA which plays central roles in both inheritance and catalysis. In this review, we present historically important and recently published articles aimed at understanding the emergence of RNA nucleosides and nucleotides on the early Earth. |
| first_indexed | 2024-12-10T06:54:46Z |
| format | Article |
| id | doaj.art-15db7a9bcd714fc8863ef288c24b9659 |
| institution | Directory Open Access Journal |
| issn | 2075-1729 |
| language | English |
| last_indexed | 2024-12-10T06:54:46Z |
| publishDate | 2018-11-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Life |
| spelling | doaj.art-15db7a9bcd714fc8863ef288c24b96592022-12-22T01:58:28ZengMDPI AGLife2075-17292018-11-01845710.3390/life8040057life8040057Exploring the Emergence of RNA Nucleosides and Nucleotides on the Early EarthAnnabelle Biscans0RNA Therapeutics Institute, University of Massachusetts Medical School, Worcester, 01605 MA, USAUnderstanding how life began is one of the most fascinating problems to solve. By approaching this enigma from a chemistry perspective, the goal is to define what series of chemical reactions could lead to the synthesis of nucleotides, amino acids, lipids, and other cellular components from simple feedstocks under prebiotically plausible conditions. It is well established that evolution of life involved RNA which plays central roles in both inheritance and catalysis. In this review, we present historically important and recently published articles aimed at understanding the emergence of RNA nucleosides and nucleotides on the early Earth.https://www.mdpi.com/2075-1729/8/4/57origin of lifeprebiotic chemistrynucleotide and nucleoside synthesis |
| spellingShingle | Annabelle Biscans Exploring the Emergence of RNA Nucleosides and Nucleotides on the Early Earth Life origin of life prebiotic chemistry nucleotide and nucleoside synthesis |
| title | Exploring the Emergence of RNA Nucleosides and Nucleotides on the Early Earth |
| title_full | Exploring the Emergence of RNA Nucleosides and Nucleotides on the Early Earth |
| title_fullStr | Exploring the Emergence of RNA Nucleosides and Nucleotides on the Early Earth |
| title_full_unstemmed | Exploring the Emergence of RNA Nucleosides and Nucleotides on the Early Earth |
| title_short | Exploring the Emergence of RNA Nucleosides and Nucleotides on the Early Earth |
| title_sort | exploring the emergence of rna nucleosides and nucleotides on the early earth |
| topic | origin of life prebiotic chemistry nucleotide and nucleoside synthesis |
| url | https://www.mdpi.com/2075-1729/8/4/57 |
| work_keys_str_mv | AT annabellebiscans exploringtheemergenceofrnanucleosidesandnucleotidesontheearlyearth |