Shape Anisotropic Iron Oxide-Based Magnetic Nanoparticles: Synthesis and Biomedical Applications
Research on iron oxide-based magnetic nanoparticles and their clinical use has been, so far, mainly focused on the spherical shape. However, efforts have been made to develop synthetic routes that produce different anisotropic shapes not only in magnetite nanoparticles, but also in other ferrites, a...
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| Format: | Article |
| Language: | English |
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MDPI AG
2020-04-01
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| Series: | International Journal of Molecular Sciences |
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| Online Access: | https://www.mdpi.com/1422-0067/21/7/2455 |
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| author | Raquel G. D. Andrade Sérgio R. S. Veloso Elisabete M. S. Castanheira |
| author_facet | Raquel G. D. Andrade Sérgio R. S. Veloso Elisabete M. S. Castanheira |
| author_sort | Raquel G. D. Andrade |
| collection | DOAJ |
| description | Research on iron oxide-based magnetic nanoparticles and their clinical use has been, so far, mainly focused on the spherical shape. However, efforts have been made to develop synthetic routes that produce different anisotropic shapes not only in magnetite nanoparticles, but also in other ferrites, as their magnetic behavior and biological activity can be improved by controlling the shape. Ferrite nanoparticles show several properties that arise from finite-size and surface effects, like high magnetization and superparamagnetism, which make them interesting for use in nanomedicine. Herein, we show recent developments on the synthesis of anisotropic ferrite nanoparticles and the importance of shape-dependent properties for biomedical applications, such as magnetic drug delivery, magnetic hyperthermia and magnetic resonance imaging. A brief discussion on toxicity of iron oxide nanoparticles is also included. |
| first_indexed | 2024-03-10T20:44:34Z |
| format | Article |
| id | doaj.art-15df83449fdb45a9868bba89dd3ebe7a |
| institution | Directory Open Access Journal |
| issn | 1661-6596 1422-0067 |
| language | English |
| last_indexed | 2024-03-10T20:44:34Z |
| publishDate | 2020-04-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | International Journal of Molecular Sciences |
| spelling | doaj.art-15df83449fdb45a9868bba89dd3ebe7a2023-11-19T20:25:38ZengMDPI AGInternational Journal of Molecular Sciences1661-65961422-00672020-04-01217245510.3390/ijms21072455Shape Anisotropic Iron Oxide-Based Magnetic Nanoparticles: Synthesis and Biomedical ApplicationsRaquel G. D. Andrade0Sérgio R. S. Veloso1Elisabete M. S. Castanheira2Centre of Physics (CFUM), University of Minho, Campus de Gualtar, 4710-057 Braga, PortugalCentre of Physics (CFUM), University of Minho, Campus de Gualtar, 4710-057 Braga, PortugalCentre of Physics (CFUM), University of Minho, Campus de Gualtar, 4710-057 Braga, PortugalResearch on iron oxide-based magnetic nanoparticles and their clinical use has been, so far, mainly focused on the spherical shape. However, efforts have been made to develop synthetic routes that produce different anisotropic shapes not only in magnetite nanoparticles, but also in other ferrites, as their magnetic behavior and biological activity can be improved by controlling the shape. Ferrite nanoparticles show several properties that arise from finite-size and surface effects, like high magnetization and superparamagnetism, which make them interesting for use in nanomedicine. Herein, we show recent developments on the synthesis of anisotropic ferrite nanoparticles and the importance of shape-dependent properties for biomedical applications, such as magnetic drug delivery, magnetic hyperthermia and magnetic resonance imaging. A brief discussion on toxicity of iron oxide nanoparticles is also included.https://www.mdpi.com/1422-0067/21/7/2455anisotropymagnetic nanoparticleshyperthermiamagnetic resonance imagingdrug delivery |
| spellingShingle | Raquel G. D. Andrade Sérgio R. S. Veloso Elisabete M. S. Castanheira Shape Anisotropic Iron Oxide-Based Magnetic Nanoparticles: Synthesis and Biomedical Applications International Journal of Molecular Sciences anisotropy magnetic nanoparticles hyperthermia magnetic resonance imaging drug delivery |
| title | Shape Anisotropic Iron Oxide-Based Magnetic Nanoparticles: Synthesis and Biomedical Applications |
| title_full | Shape Anisotropic Iron Oxide-Based Magnetic Nanoparticles: Synthesis and Biomedical Applications |
| title_fullStr | Shape Anisotropic Iron Oxide-Based Magnetic Nanoparticles: Synthesis and Biomedical Applications |
| title_full_unstemmed | Shape Anisotropic Iron Oxide-Based Magnetic Nanoparticles: Synthesis and Biomedical Applications |
| title_short | Shape Anisotropic Iron Oxide-Based Magnetic Nanoparticles: Synthesis and Biomedical Applications |
| title_sort | shape anisotropic iron oxide based magnetic nanoparticles synthesis and biomedical applications |
| topic | anisotropy magnetic nanoparticles hyperthermia magnetic resonance imaging drug delivery |
| url | https://www.mdpi.com/1422-0067/21/7/2455 |
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