The use of Hericium erinaceus and Trametes versicolor extracts in supportive treatment in oncology

Substances available in nature with potential therapeutic effects are the subject of research that raises tremendous hopes for new challenges in medicine. Fungi are the most common organisms in the ecosystem and the most interesting in this respect. This review discusses two species of edible fungi,...

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Main Authors: Winder Mateusz, Bulska-Będkowska Weronika, Chudek Jerzy
Format: Article
Language:English
Published: Sciendo 2021-03-01
Series:Acta Pharmaceutica
Subjects:
Online Access:https://doi.org/10.2478/acph-2021-0007
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author Winder Mateusz
Bulska-Będkowska Weronika
Chudek Jerzy
author_facet Winder Mateusz
Bulska-Będkowska Weronika
Chudek Jerzy
author_sort Winder Mateusz
collection DOAJ
description Substances available in nature with potential therapeutic effects are the subject of research that raises tremendous hopes for new challenges in medicine. Fungi are the most common organisms in the ecosystem and the most interesting in this respect. This review discusses two species of edible fungi, used for centuries in Eastern natural medicine, with the best-documented effect – Hericium erinaceus (He) and Trametes versicolor (Tv). The results of in vivo and in vitro studies conducted on mice and human cell lines demonstrate immunomodulatory, potentially, anticancer, anti-inflammatory and neuroregenerative effects of substances isolated from these fungi. The substances contained in the extracts of He and Tv seem to have immunomodulatory effects that may support chemotherapy. The use of these extracts is justified stronger than the other supportive treat ments based on supplements.
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spelling doaj.art-15e0b92b84634cae9c03419bd13be57e2025-02-02T09:44:23ZengSciendoActa Pharmaceutica1846-95582021-03-0171111610.2478/acph-2021-0007acph-2021-0007The use of Hericium erinaceus and Trametes versicolor extracts in supportive treatment in oncologyWinder Mateusz0Bulska-Będkowska Weronika1Chudek Jerzy2Department of Internal Medicine and Oncological Chemotherapy, Medical University of SilesiaKatowice40-027, PolandDepartment of Internal Medicine and Oncological Chemotherapy, Medical University of SilesiaKatowice40-027, PolandDepartment of Internal Medicine and Oncological Chemotherapy, Medical University of SilesiaKatowice40-027, PolandSubstances available in nature with potential therapeutic effects are the subject of research that raises tremendous hopes for new challenges in medicine. Fungi are the most common organisms in the ecosystem and the most interesting in this respect. This review discusses two species of edible fungi, used for centuries in Eastern natural medicine, with the best-documented effect – Hericium erinaceus (He) and Trametes versicolor (Tv). The results of in vivo and in vitro studies conducted on mice and human cell lines demonstrate immunomodulatory, potentially, anticancer, anti-inflammatory and neuroregenerative effects of substances isolated from these fungi. The substances contained in the extracts of He and Tv seem to have immunomodulatory effects that may support chemotherapy. The use of these extracts is justified stronger than the other supportive treat ments based on supplements.https://doi.org/10.2478/acph-2021-0007hericium erinaceustrametes versicoloroncologyfungiimmunomodulation
spellingShingle Winder Mateusz
Bulska-Będkowska Weronika
Chudek Jerzy
The use of Hericium erinaceus and Trametes versicolor extracts in supportive treatment in oncology
Acta Pharmaceutica
hericium erinaceus
trametes versicolor
oncology
fungi
immunomodulation
title The use of Hericium erinaceus and Trametes versicolor extracts in supportive treatment in oncology
title_full The use of Hericium erinaceus and Trametes versicolor extracts in supportive treatment in oncology
title_fullStr The use of Hericium erinaceus and Trametes versicolor extracts in supportive treatment in oncology
title_full_unstemmed The use of Hericium erinaceus and Trametes versicolor extracts in supportive treatment in oncology
title_short The use of Hericium erinaceus and Trametes versicolor extracts in supportive treatment in oncology
title_sort use of hericium erinaceus and trametes versicolor extracts in supportive treatment in oncology
topic hericium erinaceus
trametes versicolor
oncology
fungi
immunomodulation
url https://doi.org/10.2478/acph-2021-0007
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