Utilization of a silkworm model for understanding host-pathogen interactions
Studies of the interactions between humans and pathogenic microorganisms require adequate representative animal infection models. Further, the availability of invertebrate models overcomes the ethical and financial issues of studying vertebrate materials. Insects have an innate immune system that is...
| Main Authors: | , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
University of Modena and Reggio Emilia
2012-09-01
|
| Series: | Invertebrate Survival Journal |
| Subjects: | |
| Online Access: | https://isj02.unimore.it/index.php/ISJ/article/view/270 |
| _version_ | 1819279759956246528 |
|---|---|
| author | C Kaito H Yoshikai K Sekimizu |
| author_facet | C Kaito H Yoshikai K Sekimizu |
| author_sort | C Kaito |
| collection | DOAJ |
| description | Studies of the interactions between humans and pathogenic microorganisms require adequate representative animal infection models. Further, the availability of invertebrate models overcomes the ethical and financial issues of studying vertebrate materials. Insects have an innate immune system that is conserved in mammals. The recent utilization of silkworms as an animal infection model led to the identification of novel virulence genes of human pathogenic microorganisms and novel innate immune factors in the silkworm. The silkworm infection model is effective for identifying and evaluating novel factors involved in host-pathogen interactions. |
| first_indexed | 2024-12-24T00:33:01Z |
| format | Article |
| id | doaj.art-15e2624638334f80b9b36e5b93d536bb |
| institution | Directory Open Access Journal |
| issn | 1824-307X |
| language | English |
| last_indexed | 2024-12-24T00:33:01Z |
| publishDate | 2012-09-01 |
| publisher | University of Modena and Reggio Emilia |
| record_format | Article |
| series | Invertebrate Survival Journal |
| spelling | doaj.art-15e2624638334f80b9b36e5b93d536bb2022-12-21T17:24:12ZengUniversity of Modena and Reggio EmiliaInvertebrate Survival Journal1824-307X2012-09-0192Utilization of a silkworm model for understanding host-pathogen interactionsC Kaito0H Yoshikai1K Sekimizu2Graduate School of Pharmaceutical Sciences, The University of Tokyo, Tokyo, JapanGraduate School of Pharmaceutical Sciences, The University of Tokyo, Tokyo, JapanGraduate School of Pharmaceutical Sciences, The University of Tokyo, Tokyo, JapanStudies of the interactions between humans and pathogenic microorganisms require adequate representative animal infection models. Further, the availability of invertebrate models overcomes the ethical and financial issues of studying vertebrate materials. Insects have an innate immune system that is conserved in mammals. The recent utilization of silkworms as an animal infection model led to the identification of novel virulence genes of human pathogenic microorganisms and novel innate immune factors in the silkworm. The silkworm infection model is effective for identifying and evaluating novel factors involved in host-pathogen interactions.https://isj02.unimore.it/index.php/ISJ/article/view/270insect modelinnate immune factorbacteriafungivirulence factor |
| spellingShingle | C Kaito H Yoshikai K Sekimizu Utilization of a silkworm model for understanding host-pathogen interactions Invertebrate Survival Journal insect model innate immune factor bacteria fungi virulence factor |
| title | Utilization of a silkworm model for understanding host-pathogen interactions |
| title_full | Utilization of a silkworm model for understanding host-pathogen interactions |
| title_fullStr | Utilization of a silkworm model for understanding host-pathogen interactions |
| title_full_unstemmed | Utilization of a silkworm model for understanding host-pathogen interactions |
| title_short | Utilization of a silkworm model for understanding host-pathogen interactions |
| title_sort | utilization of a silkworm model for understanding host pathogen interactions |
| topic | insect model innate immune factor bacteria fungi virulence factor |
| url | https://isj02.unimore.it/index.php/ISJ/article/view/270 |
| work_keys_str_mv | AT ckaito utilizationofasilkwormmodelforunderstandinghostpathogeninteractions AT hyoshikai utilizationofasilkwormmodelforunderstandinghostpathogeninteractions AT ksekimizu utilizationofasilkwormmodelforunderstandinghostpathogeninteractions |