A Case of Concomitant Psoriatic Exfoliative Dermatitis and Pulmonary TB with Adverse Drug Reaction to Rifampicin

Erythroderma or exfoliative dermatitis is scaling and erythema of skin involving more than 90% of total skin surface area and is a serious and difficult condition to treat because of large areas of involvement and multiple associated complications. Psoriasis is an important cause of exfoliative de...

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Main Authors: Neethu Mary George, Veena Thimmappa, Narendra Gangaiah, Amruthavalli Potlapati
Format: Article
Language:English
Published: JCDR Research and Publications Private Limited 2018-11-01
Series:Journal of Clinical and Diagnostic Research
Subjects:
Online Access:https://jcdr.net/articles/PDF/12303/37858_CE[Ra1]_F(SL)_PF1(AJ_RK1)_PN(P).pdf
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author Neethu Mary George
Veena Thimmappa
Narendra Gangaiah
Amruthavalli Potlapati
author_facet Neethu Mary George
Veena Thimmappa
Narendra Gangaiah
Amruthavalli Potlapati
author_sort Neethu Mary George
collection DOAJ
description Erythroderma or exfoliative dermatitis is scaling and erythema of skin involving more than 90% of total skin surface area and is a serious and difficult condition to treat because of large areas of involvement and multiple associated complications. Psoriasis is an important cause of exfoliative dermatitis and so is adverse drug reaction. Pulmonary tuberculosis, common in India, is usually ruled out before starting any systemic treatment like immunosuppressants in the latter. Development of tuberculosis in a psoriasis patient is a challenging situation wherein the clinician has to look for the pros and cons before choosing each step in management as one can aggravate the other. The condition becomes more troublesome if it is superadded by adverse drug reaction to one of the Antitubercular (ATT) drugs. Here, authors present a case with psoriatic exfoliative dermatitis, psoriatic arthritis and pulmonary tuberculosis with adverse drug reaction to Rifampicin from Category 1 ATT; which was identified following a drug-rechallenge test and eventual management of all the conditions concurrently.
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spelling doaj.art-15e39c1ca2af4a31a166e441474f5ab12022-12-22T03:49:48ZengJCDR Research and Publications Private LimitedJournal of Clinical and Diagnostic Research2249-782X0973-709X2018-11-011211WD01WD0310.7860/JCDR/2018/37858.12303A Case of Concomitant Psoriatic Exfoliative Dermatitis and Pulmonary TB with Adverse Drug Reaction to RifampicinNeethu Mary George0Veena Thimmappa1Narendra Gangaiah2Amruthavalli Potlapati3Junior Resident, Department of Dermatology, Sri Siddhartha Medical College, Tumkur, Karnataka, India.Assistant Professor, Department of Dermatology, Sri Siddhartha Medical College, Tumkur, Karnataka, India.Professor and Head, Department of Dermatology, Sri Siddhartha Medical College, Tumkur, Karnataka, India.Assistant Professor, Department of Dermatology, Sri Siddhartha Medical College, Tumkur, Karnataka, India.Erythroderma or exfoliative dermatitis is scaling and erythema of skin involving more than 90% of total skin surface area and is a serious and difficult condition to treat because of large areas of involvement and multiple associated complications. Psoriasis is an important cause of exfoliative dermatitis and so is adverse drug reaction. Pulmonary tuberculosis, common in India, is usually ruled out before starting any systemic treatment like immunosuppressants in the latter. Development of tuberculosis in a psoriasis patient is a challenging situation wherein the clinician has to look for the pros and cons before choosing each step in management as one can aggravate the other. The condition becomes more troublesome if it is superadded by adverse drug reaction to one of the Antitubercular (ATT) drugs. Here, authors present a case with psoriatic exfoliative dermatitis, psoriatic arthritis and pulmonary tuberculosis with adverse drug reaction to Rifampicin from Category 1 ATT; which was identified following a drug-rechallenge test and eventual management of all the conditions concurrently.https://jcdr.net/articles/PDF/12303/37858_CE[Ra1]_F(SL)_PF1(AJ_RK1)_PN(P).pdfdrug rechallenge testerythrodermapsoriatic arthritistuberculosis
spellingShingle Neethu Mary George
Veena Thimmappa
Narendra Gangaiah
Amruthavalli Potlapati
A Case of Concomitant Psoriatic Exfoliative Dermatitis and Pulmonary TB with Adverse Drug Reaction to Rifampicin
Journal of Clinical and Diagnostic Research
drug rechallenge test
erythroderma
psoriatic arthritis
tuberculosis
title A Case of Concomitant Psoriatic Exfoliative Dermatitis and Pulmonary TB with Adverse Drug Reaction to Rifampicin
title_full A Case of Concomitant Psoriatic Exfoliative Dermatitis and Pulmonary TB with Adverse Drug Reaction to Rifampicin
title_fullStr A Case of Concomitant Psoriatic Exfoliative Dermatitis and Pulmonary TB with Adverse Drug Reaction to Rifampicin
title_full_unstemmed A Case of Concomitant Psoriatic Exfoliative Dermatitis and Pulmonary TB with Adverse Drug Reaction to Rifampicin
title_short A Case of Concomitant Psoriatic Exfoliative Dermatitis and Pulmonary TB with Adverse Drug Reaction to Rifampicin
title_sort case of concomitant psoriatic exfoliative dermatitis and pulmonary tb with adverse drug reaction to rifampicin
topic drug rechallenge test
erythroderma
psoriatic arthritis
tuberculosis
url https://jcdr.net/articles/PDF/12303/37858_CE[Ra1]_F(SL)_PF1(AJ_RK1)_PN(P).pdf
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