A Case of Concomitant Psoriatic Exfoliative Dermatitis and Pulmonary TB with Adverse Drug Reaction to Rifampicin
Erythroderma or exfoliative dermatitis is scaling and erythema of skin involving more than 90% of total skin surface area and is a serious and difficult condition to treat because of large areas of involvement and multiple associated complications. Psoriasis is an important cause of exfoliative de...
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JCDR Research and Publications Private Limited
2018-11-01
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Series: | Journal of Clinical and Diagnostic Research |
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Online Access: | https://jcdr.net/articles/PDF/12303/37858_CE[Ra1]_F(SL)_PF1(AJ_RK1)_PN(P).pdf |
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author | Neethu Mary George Veena Thimmappa Narendra Gangaiah Amruthavalli Potlapati |
author_facet | Neethu Mary George Veena Thimmappa Narendra Gangaiah Amruthavalli Potlapati |
author_sort | Neethu Mary George |
collection | DOAJ |
description | Erythroderma or exfoliative dermatitis is scaling and erythema of skin involving more than 90% of total skin surface area and is a
serious and difficult condition to treat because of large areas of involvement and multiple associated complications. Psoriasis is
an important cause of exfoliative dermatitis and so is adverse drug reaction. Pulmonary tuberculosis, common in India, is usually
ruled out before starting any systemic treatment like immunosuppressants in the latter. Development of tuberculosis in a psoriasis
patient is a challenging situation wherein the clinician has to look for the pros and cons before choosing each step in management
as one can aggravate the other. The condition becomes more troublesome if it is superadded by adverse drug reaction to one of
the Antitubercular (ATT) drugs. Here, authors present a case with psoriatic exfoliative dermatitis, psoriatic arthritis and pulmonary
tuberculosis with adverse drug reaction to Rifampicin from Category 1 ATT; which was identified following a drug-rechallenge test
and eventual management of all the conditions concurrently. |
first_indexed | 2024-04-12T03:23:38Z |
format | Article |
id | doaj.art-15e39c1ca2af4a31a166e441474f5ab1 |
institution | Directory Open Access Journal |
issn | 2249-782X 0973-709X |
language | English |
last_indexed | 2024-04-12T03:23:38Z |
publishDate | 2018-11-01 |
publisher | JCDR Research and Publications Private Limited |
record_format | Article |
series | Journal of Clinical and Diagnostic Research |
spelling | doaj.art-15e39c1ca2af4a31a166e441474f5ab12022-12-22T03:49:48ZengJCDR Research and Publications Private LimitedJournal of Clinical and Diagnostic Research2249-782X0973-709X2018-11-011211WD01WD0310.7860/JCDR/2018/37858.12303A Case of Concomitant Psoriatic Exfoliative Dermatitis and Pulmonary TB with Adverse Drug Reaction to RifampicinNeethu Mary George0Veena Thimmappa1Narendra Gangaiah2Amruthavalli Potlapati3Junior Resident, Department of Dermatology, Sri Siddhartha Medical College, Tumkur, Karnataka, India.Assistant Professor, Department of Dermatology, Sri Siddhartha Medical College, Tumkur, Karnataka, India.Professor and Head, Department of Dermatology, Sri Siddhartha Medical College, Tumkur, Karnataka, India.Assistant Professor, Department of Dermatology, Sri Siddhartha Medical College, Tumkur, Karnataka, India.Erythroderma or exfoliative dermatitis is scaling and erythema of skin involving more than 90% of total skin surface area and is a serious and difficult condition to treat because of large areas of involvement and multiple associated complications. Psoriasis is an important cause of exfoliative dermatitis and so is adverse drug reaction. Pulmonary tuberculosis, common in India, is usually ruled out before starting any systemic treatment like immunosuppressants in the latter. Development of tuberculosis in a psoriasis patient is a challenging situation wherein the clinician has to look for the pros and cons before choosing each step in management as one can aggravate the other. The condition becomes more troublesome if it is superadded by adverse drug reaction to one of the Antitubercular (ATT) drugs. Here, authors present a case with psoriatic exfoliative dermatitis, psoriatic arthritis and pulmonary tuberculosis with adverse drug reaction to Rifampicin from Category 1 ATT; which was identified following a drug-rechallenge test and eventual management of all the conditions concurrently.https://jcdr.net/articles/PDF/12303/37858_CE[Ra1]_F(SL)_PF1(AJ_RK1)_PN(P).pdfdrug rechallenge testerythrodermapsoriatic arthritistuberculosis |
spellingShingle | Neethu Mary George Veena Thimmappa Narendra Gangaiah Amruthavalli Potlapati A Case of Concomitant Psoriatic Exfoliative Dermatitis and Pulmonary TB with Adverse Drug Reaction to Rifampicin Journal of Clinical and Diagnostic Research drug rechallenge test erythroderma psoriatic arthritis tuberculosis |
title | A Case of Concomitant Psoriatic Exfoliative Dermatitis and Pulmonary TB with Adverse Drug Reaction to Rifampicin |
title_full | A Case of Concomitant Psoriatic Exfoliative Dermatitis and Pulmonary TB with Adverse Drug Reaction to Rifampicin |
title_fullStr | A Case of Concomitant Psoriatic Exfoliative Dermatitis and Pulmonary TB with Adverse Drug Reaction to Rifampicin |
title_full_unstemmed | A Case of Concomitant Psoriatic Exfoliative Dermatitis and Pulmonary TB with Adverse Drug Reaction to Rifampicin |
title_short | A Case of Concomitant Psoriatic Exfoliative Dermatitis and Pulmonary TB with Adverse Drug Reaction to Rifampicin |
title_sort | case of concomitant psoriatic exfoliative dermatitis and pulmonary tb with adverse drug reaction to rifampicin |
topic | drug rechallenge test erythroderma psoriatic arthritis tuberculosis |
url | https://jcdr.net/articles/PDF/12303/37858_CE[Ra1]_F(SL)_PF1(AJ_RK1)_PN(P).pdf |
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