Improvement of Low Luminance Visual Acuity in Patients with Chronic Central Serous Chorioretinopathy after Half-Dose Verteporfin Photodynamic Therapy
Patients with central serous chorioretinopathy (CSC) often complain of visual difficulties under low luminance conditions. In this study, we evaluated low luminance visual acuity (LLVA) after half-dose verteporfin photodynamic therapy (hdPDT) in eyes with CSC. The study included eight eyes of eight...
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MDPI AG
2020-12-01
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| Series: | Journal of Clinical Medicine |
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| Online Access: | https://www.mdpi.com/2077-0383/9/12/3980 |
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| author | Kyoko Fujita Kei Shinoda Yutaka Imamura Celso Soiti Matsumoto Koichi Oda |
| author_facet | Kyoko Fujita Kei Shinoda Yutaka Imamura Celso Soiti Matsumoto Koichi Oda |
| author_sort | Kyoko Fujita |
| collection | DOAJ |
| description | Patients with central serous chorioretinopathy (CSC) often complain of visual difficulties under low luminance conditions. In this study, we evaluated low luminance visual acuity (LLVA) after half-dose verteporfin photodynamic therapy (hdPDT) in eyes with CSC. The study included eight eyes of eight patients with chronic CSC that underwent hdPDT. The best-corrected visual acuity, LLVA and optical coherence tomography (OCT) findings were evaluated at baseline, and at 1, 3, 6, 9, and 12 months after hdPDT. LLVA was measured at six levels of background luminance. Serous retinal detachment was completely resolved in all eyes. Although the mean LLVA at 1 month did not improve significantly compared to baseline at all luminance levels, significant improvements were observed at 3, 6, 9, and 12 months (<i>p</i> < 0.05). In OCT images, although the ellipsoid zone was not detectable in all eyes before hdPDT, it was observed in 2 eyes at 1 month, in 7 eyes at 3 months, and in all eyes from 6 months. The LLVA and the ellipsoid zone improved similarly with postoperative time courses. In conclusion, hdPDT improves LLVA in eyes with chronic CSC. The recovery of the ellipsoid zone may play a part in improving LLVA after hdPDT. |
| first_indexed | 2024-03-10T14:13:19Z |
| format | Article |
| id | doaj.art-15e5333a3a68455382f5fcae15f386e9 |
| institution | Directory Open Access Journal |
| issn | 2077-0383 |
| language | English |
| last_indexed | 2024-03-10T14:13:19Z |
| publishDate | 2020-12-01 |
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| record_format | Article |
| series | Journal of Clinical Medicine |
| spelling | doaj.art-15e5333a3a68455382f5fcae15f386e92023-11-20T23:57:35ZengMDPI AGJournal of Clinical Medicine2077-03832020-12-01912398010.3390/jcm9123980Improvement of Low Luminance Visual Acuity in Patients with Chronic Central Serous Chorioretinopathy after Half-Dose Verteporfin Photodynamic TherapyKyoko Fujita0Kei Shinoda1Yutaka Imamura2Celso Soiti Matsumoto3Koichi Oda4Department of Opthalmology, Aichi Medical University School of Medicine, Aichi 480-1195, JapanDepartment of Ophthalmology, Saitama Medical University School of Medicine, Saitama 350-0495, JapanDepartment of Ophthalmology, Teikyo University School of Medicine, University Hospital Mizonokuchi, Kanagawa 213-8507, JapanDepartment of Ophthalmology, Teikyo University School of Medicine, University Hospital Itabashi, Tokyo 173-8606, JapanDepartment of Communication, Tokyo Woman’s Christian University, Tokyo 167-8585, JapanPatients with central serous chorioretinopathy (CSC) often complain of visual difficulties under low luminance conditions. In this study, we evaluated low luminance visual acuity (LLVA) after half-dose verteporfin photodynamic therapy (hdPDT) in eyes with CSC. The study included eight eyes of eight patients with chronic CSC that underwent hdPDT. The best-corrected visual acuity, LLVA and optical coherence tomography (OCT) findings were evaluated at baseline, and at 1, 3, 6, 9, and 12 months after hdPDT. LLVA was measured at six levels of background luminance. Serous retinal detachment was completely resolved in all eyes. Although the mean LLVA at 1 month did not improve significantly compared to baseline at all luminance levels, significant improvements were observed at 3, 6, 9, and 12 months (<i>p</i> < 0.05). In OCT images, although the ellipsoid zone was not detectable in all eyes before hdPDT, it was observed in 2 eyes at 1 month, in 7 eyes at 3 months, and in all eyes from 6 months. The LLVA and the ellipsoid zone improved similarly with postoperative time courses. In conclusion, hdPDT improves LLVA in eyes with chronic CSC. The recovery of the ellipsoid zone may play a part in improving LLVA after hdPDT.https://www.mdpi.com/2077-0383/9/12/3980central serous chorioretinopathylow luminance visual acuityphotodynamic therapyellipsoid zone |
| spellingShingle | Kyoko Fujita Kei Shinoda Yutaka Imamura Celso Soiti Matsumoto Koichi Oda Improvement of Low Luminance Visual Acuity in Patients with Chronic Central Serous Chorioretinopathy after Half-Dose Verteporfin Photodynamic Therapy Journal of Clinical Medicine central serous chorioretinopathy low luminance visual acuity photodynamic therapy ellipsoid zone |
| title | Improvement of Low Luminance Visual Acuity in Patients with Chronic Central Serous Chorioretinopathy after Half-Dose Verteporfin Photodynamic Therapy |
| title_full | Improvement of Low Luminance Visual Acuity in Patients with Chronic Central Serous Chorioretinopathy after Half-Dose Verteporfin Photodynamic Therapy |
| title_fullStr | Improvement of Low Luminance Visual Acuity in Patients with Chronic Central Serous Chorioretinopathy after Half-Dose Verteporfin Photodynamic Therapy |
| title_full_unstemmed | Improvement of Low Luminance Visual Acuity in Patients with Chronic Central Serous Chorioretinopathy after Half-Dose Verteporfin Photodynamic Therapy |
| title_short | Improvement of Low Luminance Visual Acuity in Patients with Chronic Central Serous Chorioretinopathy after Half-Dose Verteporfin Photodynamic Therapy |
| title_sort | improvement of low luminance visual acuity in patients with chronic central serous chorioretinopathy after half dose verteporfin photodynamic therapy |
| topic | central serous chorioretinopathy low luminance visual acuity photodynamic therapy ellipsoid zone |
| url | https://www.mdpi.com/2077-0383/9/12/3980 |
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