Cerebral larval infection presenting as delayed encephalopathy and nonconvulsive status epilepticus: a case report
Adult cerebral Toxocara canis larval infections are rare. Humans are infected by contacting soil that contains infectious eggs or by eating undercooked meat. We encountered a patient with cerebral T. canis infection who showed recurrent altered mentality with nonconvulsive status epilepticus (NCSE)....
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
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Korean Encephalitis and Neuroinflammation Society
2021-04-01
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| Series: | Encephalitis |
| Subjects: | |
| Online Access: | http://www.encephalitisjournal.org/upload/pdf/encephalitis-2021-00024.pdf |
| _version_ | 1819128820790198272 |
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| author | Jung-Ju Lee Kyusik Kang Woong-Woo Lee Byung-Kun Kim Jong-Moo Park Ohyun Kwon Soohyun Cho |
| author_facet | Jung-Ju Lee Kyusik Kang Woong-Woo Lee Byung-Kun Kim Jong-Moo Park Ohyun Kwon Soohyun Cho |
| author_sort | Jung-Ju Lee |
| collection | DOAJ |
| description | Adult cerebral Toxocara canis larval infections are rare. Humans are infected by contacting soil that contains infectious eggs or by eating undercooked meat. We encountered a patient with cerebral T. canis infection who showed recurrent altered mentality with nonconvulsive status epilepticus (NCSE). A 71-year-old male was admitted with complaints of drowsy mentality and abnormal behavior. Magnetic resonance imaging revealed non-enhanced multiple gliosis and calcified lesions. Electroencephalography revealed NCSE, which was cured with valproate. However, he was readmitted because of recurrence of symptoms. On cerebrospinal fluid examination, T. canis antibodies were observed. Subsequently, he was treated with albendazole and corticosteroids. Although corticosteroid improved his symptoms, the therapy could not be continued because the patient developed septic shock. This is the first report of cerebral T. canis larval infection presenting as delayed encephalopathy and NCSE. In patients with unexplainable progressive encephalopathy, particularly when gliosis or calcified lesions are observed on neuroimaging, cerebral T. canis larval infection should be considered and treated promptly. |
| first_indexed | 2024-12-22T08:33:54Z |
| format | Article |
| id | doaj.art-15ea8031040b4d24bba15845408ce456 |
| institution | Directory Open Access Journal |
| issn | 2765-4559 2734-1461 |
| language | English |
| last_indexed | 2024-12-22T08:33:54Z |
| publishDate | 2021-04-01 |
| publisher | Korean Encephalitis and Neuroinflammation Society |
| record_format | Article |
| series | Encephalitis |
| spelling | doaj.art-15ea8031040b4d24bba15845408ce4562022-12-21T18:32:24ZengKorean Encephalitis and Neuroinflammation SocietyEncephalitis2765-45592734-14612021-04-0112515510.47936/encephalitis.2021.0002412Cerebral larval infection presenting as delayed encephalopathy and nonconvulsive status epilepticus: a case reportJung-Ju LeeKyusik Kang0Woong-Woo Lee1Byung-Kun Kim2Jong-Moo Park3Ohyun Kwon4Soohyun Cho5 Department of Neurology, Nowon Eulji Medical Center, Eulji University, Seoul, Korea Department of Neurology, Nowon Eulji Medical Center, Eulji University, Seoul, Korea Department of Neurology, Nowon Eulji Medical Center, Eulji University, Seoul, Korea Department of Neurology, Nowon Eulji Medical Center, Eulji University, Seoul, Korea Department of Neurology, Nowon Eulji Medical Center, Eulji University, Seoul, Korea Department of Neurology, Nowon Eulji Medical Center, Eulji University, Seoul, KoreaAdult cerebral Toxocara canis larval infections are rare. Humans are infected by contacting soil that contains infectious eggs or by eating undercooked meat. We encountered a patient with cerebral T. canis infection who showed recurrent altered mentality with nonconvulsive status epilepticus (NCSE). A 71-year-old male was admitted with complaints of drowsy mentality and abnormal behavior. Magnetic resonance imaging revealed non-enhanced multiple gliosis and calcified lesions. Electroencephalography revealed NCSE, which was cured with valproate. However, he was readmitted because of recurrence of symptoms. On cerebrospinal fluid examination, T. canis antibodies were observed. Subsequently, he was treated with albendazole and corticosteroids. Although corticosteroid improved his symptoms, the therapy could not be continued because the patient developed septic shock. This is the first report of cerebral T. canis larval infection presenting as delayed encephalopathy and NCSE. In patients with unexplainable progressive encephalopathy, particularly when gliosis or calcified lesions are observed on neuroimaging, cerebral T. canis larval infection should be considered and treated promptly.http://www.encephalitisjournal.org/upload/pdf/encephalitis-2021-00024.pdfstatus epilepticusalbendazoleadrenal cortex hormones |
| spellingShingle | Jung-Ju Lee Kyusik Kang Woong-Woo Lee Byung-Kun Kim Jong-Moo Park Ohyun Kwon Soohyun Cho Cerebral larval infection presenting as delayed encephalopathy and nonconvulsive status epilepticus: a case report Encephalitis status epilepticus albendazole adrenal cortex hormones |
| title | Cerebral larval infection presenting as delayed encephalopathy and nonconvulsive status epilepticus: a case report |
| title_full | Cerebral larval infection presenting as delayed encephalopathy and nonconvulsive status epilepticus: a case report |
| title_fullStr | Cerebral larval infection presenting as delayed encephalopathy and nonconvulsive status epilepticus: a case report |
| title_full_unstemmed | Cerebral larval infection presenting as delayed encephalopathy and nonconvulsive status epilepticus: a case report |
| title_short | Cerebral larval infection presenting as delayed encephalopathy and nonconvulsive status epilepticus: a case report |
| title_sort | cerebral larval infection presenting as delayed encephalopathy and nonconvulsive status epilepticus a case report |
| topic | status epilepticus albendazole adrenal cortex hormones |
| url | http://www.encephalitisjournal.org/upload/pdf/encephalitis-2021-00024.pdf |
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