Characteristics of Febrile Convulsions and The Association Between Ketonuria and Febrile Convulsions

  Background: Febrile seizures are common and mostly benign. There is growing evidence that ketone bodies derived from fatty acid oxidation during fasting or consumption of high-fat diets can exert broad neuroprotective effects, including anti-convulsant effects. Objective: To determine the c...

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Main Authors: Najdat Sh Mahmood, Oday Abood Khalil, Jalil Ibrahim Alezzi
Format: Article
Language:English
Published: College of medicine/ University of Diyala 2021-04-01
Series:Diyala Journal of Medicine
Subjects:
Online Access:http://djm.uodiyala.edu.iq/index.php/djm/article/view/711
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author Najdat Sh Mahmood
Oday Abood Khalil
Jalil Ibrahim Alezzi
author_facet Najdat Sh Mahmood
Oday Abood Khalil
Jalil Ibrahim Alezzi
author_sort Najdat Sh Mahmood
collection DOAJ
description   Background: Febrile seizures are common and mostly benign. There is growing evidence that ketone bodies derived from fatty acid oxidation during fasting or consumption of high-fat diets can exert broad neuroprotective effects, including anti-convulsant effects. Objective: To determine the characteristics of febrile convulsions and the relationship between ketonuria and febrile convulsions. Patients and Methods: A cross-sectional comparative study was done between May 2018 – December 2019 at Al-Batool teaching hospital. The data included 100 children aged between (6- 60 months) admitted to the emergency unit, 50 % of them were having a febrile convulsion, while the others were presented with fever without a seizure. Blood samples were measured for serum glucose and urine samples were taken for level of ketone bodies (KB) and analyzed by reagent strip test. Statistical analysis was done by using SPSS version 21, level of association between variables was tested by Chi-square at 0.05. Results: Febrile convulsions occur equally in males and females and more likely in children less than 18 months of age (P value=0.157). Causes of fever in children with febrile convulsion were mostly respiratory causes (p value=0. 000). The incidence of hypoglycemia and ketonuria were slightly more common in the non-convulsive group of the study to be statistically insignificant (p- values were 0.169 and 0.275, respectively). Conclusion: The febrile convulsions affect equally males and females and the major cause of fever was respiratory infections. There is no significant relationship between ketonuria and the occurrence of febrile convulsions.
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spelling doaj.art-15ec0365b8cc4bd18dc97ee7281b94182023-11-24T23:22:41ZengCollege of medicine/ University of DiyalaDiyala Journal of Medicine2219-97642617-89822021-04-01201Characteristics of Febrile Convulsions and The Association Between Ketonuria and Febrile ConvulsionsNajdat Sh Mahmood Oday Abood KhalilJalil Ibrahim Alezzi   Background: Febrile seizures are common and mostly benign. There is growing evidence that ketone bodies derived from fatty acid oxidation during fasting or consumption of high-fat diets can exert broad neuroprotective effects, including anti-convulsant effects. Objective: To determine the characteristics of febrile convulsions and the relationship between ketonuria and febrile convulsions. Patients and Methods: A cross-sectional comparative study was done between May 2018 – December 2019 at Al-Batool teaching hospital. The data included 100 children aged between (6- 60 months) admitted to the emergency unit, 50 % of them were having a febrile convulsion, while the others were presented with fever without a seizure. Blood samples were measured for serum glucose and urine samples were taken for level of ketone bodies (KB) and analyzed by reagent strip test. Statistical analysis was done by using SPSS version 21, level of association between variables was tested by Chi-square at 0.05. Results: Febrile convulsions occur equally in males and females and more likely in children less than 18 months of age (P value=0.157). Causes of fever in children with febrile convulsion were mostly respiratory causes (p value=0. 000). The incidence of hypoglycemia and ketonuria were slightly more common in the non-convulsive group of the study to be statistically insignificant (p- values were 0.169 and 0.275, respectively). Conclusion: The febrile convulsions affect equally males and females and the major cause of fever was respiratory infections. There is no significant relationship between ketonuria and the occurrence of febrile convulsions. http://djm.uodiyala.edu.iq/index.php/djm/article/view/711Febrile convulsion; Ketonuria; Children
spellingShingle Najdat Sh Mahmood
Oday Abood Khalil
Jalil Ibrahim Alezzi
Characteristics of Febrile Convulsions and The Association Between Ketonuria and Febrile Convulsions
Diyala Journal of Medicine
Febrile convulsion; Ketonuria; Children
title Characteristics of Febrile Convulsions and The Association Between Ketonuria and Febrile Convulsions
title_full Characteristics of Febrile Convulsions and The Association Between Ketonuria and Febrile Convulsions
title_fullStr Characteristics of Febrile Convulsions and The Association Between Ketonuria and Febrile Convulsions
title_full_unstemmed Characteristics of Febrile Convulsions and The Association Between Ketonuria and Febrile Convulsions
title_short Characteristics of Febrile Convulsions and The Association Between Ketonuria and Febrile Convulsions
title_sort characteristics of febrile convulsions and the association between ketonuria and febrile convulsions
topic Febrile convulsion; Ketonuria; Children
url http://djm.uodiyala.edu.iq/index.php/djm/article/view/711
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