Comprehensive Analysis of the Immunogenomics of Triple-Negative Breast Cancer Brain Metastases From LCCC1419

Comprehensive Analysis of the Immunogenomics of Triple-Negative Breast Cancer Brain Metastases From LCCC1419

BackgroundTriple negative breast cancer (TNBC) is an aggressive variant of breast cancer that lacks the expression of estrogen and progesterone receptors (ER and PR) and HER2. Nearly 50% of patients with advanced TNBC will develop brain metastases (BrM), commonly with progressive extracranial diseas...

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Bibliographic Details
Main Authors: Eric D. Routh, Amanda E. D. Van Swearingen, Maria J. Sambade, Steven Vensko, Marni B. McClure, Mark G. Woodcock, Shengjie Chai, Luz A. Cuaboy, Amy Wheless, Amy Garrett, Lisa A. Carey, Alan P. Hoyle, Joel S. Parker, Benjamin G. Vincent, Carey K. Anders
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-07-01
Series:Frontiers in Oncology
Subjects:
triple-negative breast cancer
brain metastases
immunogenomics
whole-exome sequencing
mRNA sequencing
biobank
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2022.818693/full

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https://www.frontiersin.org/articles/10.3389/fonc.2022.818693/full

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