Protection against Shiga Toxins
Shiga toxins consist of an A-moiety and five B-moieties able to bind the neutral glycosphingolipid globotriaosylceramide (Gb3) on the cell surface. To intoxicate cells efficiently, the toxin A-moiety has to be cleaved by furin and transported retrogradely to the Golgi apparatus and to the endoplasmi...
| Hlavní autoři: | , , , |
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| Médium: | Článek |
| Jazyk: | English |
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MDPI AG
2017-02-01
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| Edice: | Toxins |
| Témata: | |
| On-line přístup: | http://www.mdpi.com/2072-6651/9/2/44 |