Correlation between salivary biomarkers and plaque-induced gingivitis exacerbated by pregnancy
Objetive: To evaluate the correlation between salivary biomarkers (the salivary antioxidant ability, salivary level of polyphenols, and other antioxidants) with plaque-induced gingivitis exacerbated by pregnancy in pregnant and nonpregnant women. Material and Methods: For this observational study,...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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Universidad de Concepción.
2022-06-01
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| Series: | Journal of Oral Research |
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| Online Access: | https://joralres.com/index.php/JOralRes/article/view/joralres.2022.032/1048 |
| _version_ | 1828055185473142784 |
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| author | Othoniel Aragon-Martinez Karen Loredo-Escobar Juan Cepeda-Bravo Flavio Martinez-Morales Maria Gonzalez-Rivera Saray Aranda Romo |
| author_facet | Othoniel Aragon-Martinez Karen Loredo-Escobar Juan Cepeda-Bravo Flavio Martinez-Morales Maria Gonzalez-Rivera Saray Aranda Romo |
| author_sort | Othoniel Aragon-Martinez |
| collection | DOAJ |
| description | Objetive: To evaluate the correlation between salivary biomarkers (the salivary antioxidant ability, salivary level of polyphenols, and other antioxidants) with plaque-induced gingivitis exacerbated by pregnancy in pregnant and nonpregnant women.
Material and Methods: For this observational study, medical records, dental examinations, and analyses of saliva samples were carried out in pregnant and nonpregnant women. A p-value of <0.05 was considered significant.
Results: The pregnant women (n =17) exhibited a lower antioxidant capacity (p-value=0.0041), higher levels of polyphenols, gingival index, bleeding on probing, and subjects consuming mineral-enriched products (p-value from <0.0001 to 0.0466), and unchanged levels of phosphotungstic acid reactive substances, proteins, oral hygienic habits, plaque index and probing depth (p-value from 0.0683 to 0.8358), in comparison with the nonpregnant women (n=9). Also, a positive correlation between the gingival index and salivary polyphenol content was observed (r-value = 0.4087, p-value = 0.0202).
Conclusion: The salivary polyphenols correlate with plaque-induced gingivitis exacerbated by pregnancy, suggesting a deficiency of salivary antioxidant protection. |
| first_indexed | 2024-04-10T20:34:39Z |
| format | Article |
| id | doaj.art-15f44c65902248e28890585dde364860 |
| institution | Directory Open Access Journal |
| issn | 0719-2460 0719-2479 |
| language | English |
| last_indexed | 2024-04-10T20:34:39Z |
| publishDate | 2022-06-01 |
| publisher | Universidad de Concepción. |
| record_format | Article |
| series | Journal of Oral Research |
| spelling | doaj.art-15f44c65902248e28890585dde3648602023-01-24T22:38:27ZengUniversidad de Concepción.Journal of Oral Research0719-24600719-24792022-06-01113112https://doi.org/10.17126/joralres.2022.032Correlation between salivary biomarkers and plaque-induced gingivitis exacerbated by pregnancyOthoniel Aragon-Martinez0https://orcid.org/0000-0003-2298-404XKaren Loredo-Escobar1https://orcid.org/0000-0002-1816-4666Juan Cepeda-Bravo2https://orcid.org/0000-0002-6696-3796Flavio Martinez-Morales3https://orcid.org/0000-0003-0339-1089Maria Gonzalez-Rivera4Saray Aranda Romo5https://orcid.org/0000-0002-0379-9626Department of Pharmacology, School of Medicine, Autonomous University of San Luis Potosi, San Luis Potosi, Mexico.Periodontics Postgraduate Program, Dentistry School, Autonomous University of San Luis Potosi, San Luis Potosi, Mexico.Periodontics Postgraduate Program, Dentistry School, Autonomous University of San Luis Potosi, San Luis Potosi, Mexico.| Periodontics Clinic, Dentistry School, Autonomous University of San Luis Potosi, San Luis Potosi, Mexico.Department of Pharmacology, School of Medicine, Autonomous University of San Luis Potosi, San Luis Potosi, MexicoDepartment of Pharmacology, School of Medicine, Autonomous University of San Luis Potosi, San Luis Potosi, Mexico.Department of Pharmacology, School of Medicine, Autonomous University of San Luis Potosi, San Luis Potosi, MexicoObjetive: To evaluate the correlation between salivary biomarkers (the salivary antioxidant ability, salivary level of polyphenols, and other antioxidants) with plaque-induced gingivitis exacerbated by pregnancy in pregnant and nonpregnant women. Material and Methods: For this observational study, medical records, dental examinations, and analyses of saliva samples were carried out in pregnant and nonpregnant women. A p-value of <0.05 was considered significant. Results: The pregnant women (n =17) exhibited a lower antioxidant capacity (p-value=0.0041), higher levels of polyphenols, gingival index, bleeding on probing, and subjects consuming mineral-enriched products (p-value from <0.0001 to 0.0466), and unchanged levels of phosphotungstic acid reactive substances, proteins, oral hygienic habits, plaque index and probing depth (p-value from 0.0683 to 0.8358), in comparison with the nonpregnant women (n=9). Also, a positive correlation between the gingival index and salivary polyphenol content was observed (r-value = 0.4087, p-value = 0.0202). Conclusion: The salivary polyphenols correlate with plaque-induced gingivitis exacerbated by pregnancy, suggesting a deficiency of salivary antioxidant protection.https://joralres.com/index.php/JOralRes/article/view/joralres.2022.032/1048salivabiomarkersantioxidantspolyphenolspregnancyplaque-induced gingivitis |
| spellingShingle | Othoniel Aragon-Martinez Karen Loredo-Escobar Juan Cepeda-Bravo Flavio Martinez-Morales Maria Gonzalez-Rivera Saray Aranda Romo Correlation between salivary biomarkers and plaque-induced gingivitis exacerbated by pregnancy Journal of Oral Research saliva biomarkers antioxidants polyphenols pregnancy plaque-induced gingivitis |
| title | Correlation between salivary biomarkers and plaque-induced gingivitis exacerbated by pregnancy |
| title_full | Correlation between salivary biomarkers and plaque-induced gingivitis exacerbated by pregnancy |
| title_fullStr | Correlation between salivary biomarkers and plaque-induced gingivitis exacerbated by pregnancy |
| title_full_unstemmed | Correlation between salivary biomarkers and plaque-induced gingivitis exacerbated by pregnancy |
| title_short | Correlation between salivary biomarkers and plaque-induced gingivitis exacerbated by pregnancy |
| title_sort | correlation between salivary biomarkers and plaque induced gingivitis exacerbated by pregnancy |
| topic | saliva biomarkers antioxidants polyphenols pregnancy plaque-induced gingivitis |
| url | https://joralres.com/index.php/JOralRes/article/view/joralres.2022.032/1048 |
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