Polycystic Ovary Syndrome in Adolescent Period: Physical, Metabolic, and Hormonal Features
Aim: The Rotterdam criteria are used in the diagnosis of polycystic ovary syndrome (PCOS). However, since menstrual irregularities and acne are seen more frequently in adolescents, it is theoretically difficult to use the Rotterdam criteria. The aim of this study was to investigate whether the Rotte...
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| Format: | Article |
| Language: | English |
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Duzce University
2022-12-01
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| Series: | Düzce Tıp Fakültesi Dergisi |
| Subjects: | |
| Online Access: | https://dergipark.org.tr/en/download/article-file/2314640 |
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| author | Mustafa Harı Mehmet Burak Çimen Hüseyin Durukan Mahmut Bakır Koyuncu Ramazan Gen |
| author_facet | Mustafa Harı Mehmet Burak Çimen Hüseyin Durukan Mahmut Bakır Koyuncu Ramazan Gen |
| author_sort | Mustafa Harı |
| collection | DOAJ |
| description | Aim: The Rotterdam criteria are used in the diagnosis of polycystic ovary syndrome (PCOS). However, since menstrual irregularities and acne are seen more frequently in adolescents, it is theoretically difficult to use the Rotterdam criteria. The aim of this study was to investigate whether the Rotterdam criteria are sufficient for the diagnosis of PCOS in adolescence.
Material and Methods: Thirty patients and thirty healthy individuals between the ages of 16 and 18 years were included in the study. Anthropometric measurements, Ferriman Gallwey score (FGS), ultrasonographic ovarian volumes, androgens, and other hormone levels of the participants were recorded.
Results: There was a statistically significant positive correlation between the homeostatic model assessment of insulin resistance (HOMA-IR) and waist circumference/hip circumference ratio in the patient group (r=0.656, p<0.001). The mean luteinizing hormone (LH) levels of the patient group were found to be statistically significantly higher than the control group (p=0.048). The median FGS of the patient group was statistically significantly higher than the control group (p<0.001). Serum total testosterone levels of adolescent girls who have polycystic ovaries were statistically significantly higher than the ones who have not (p=0.001). The median FGS of those with polycystic ovarian appearance on ultrasonography was found to be statistically significantly higher than those without (p=0.034).
Conclusion: Among the Rotterdam diagnostic criteria, oligoanovulation, acne, and polycystic ovarian appearance on ultrasonography can be seen in healthy adolescents without PCOS. In this study, the most supportive finding for the diagnosis of PCOS was the appearance of polycystic ovaries accompanying moderate hirsutism. |
| first_indexed | 2024-03-09T08:29:27Z |
| format | Article |
| id | doaj.art-15f949751e834e589f4d4310bb4d876c |
| institution | Directory Open Access Journal |
| issn | 1307-671X |
| language | English |
| last_indexed | 2024-03-09T08:29:27Z |
| publishDate | 2022-12-01 |
| publisher | Duzce University |
| record_format | Article |
| series | Düzce Tıp Fakültesi Dergisi |
| spelling | doaj.art-15f949751e834e589f4d4310bb4d876c2023-12-02T20:23:56ZengDuzce UniversityDüzce Tıp Fakültesi Dergisi1307-671X2022-12-0124322122610.18678/dtfd.108904397Polycystic Ovary Syndrome in Adolescent Period: Physical, Metabolic, and Hormonal FeaturesMustafa Harı0Mehmet Burak Çimen1Hüseyin Durukan2Mahmut Bakır Koyuncu3Ramazan Gen4Mersin Şehir Eğitim ve Araştırma HastanesiMERSIN UNIVERSITYMERSIN UNIVERSITYMERSIN UNIVERSITYMERSIN UNIVERSITYAim: The Rotterdam criteria are used in the diagnosis of polycystic ovary syndrome (PCOS). However, since menstrual irregularities and acne are seen more frequently in adolescents, it is theoretically difficult to use the Rotterdam criteria. The aim of this study was to investigate whether the Rotterdam criteria are sufficient for the diagnosis of PCOS in adolescence. Material and Methods: Thirty patients and thirty healthy individuals between the ages of 16 and 18 years were included in the study. Anthropometric measurements, Ferriman Gallwey score (FGS), ultrasonographic ovarian volumes, androgens, and other hormone levels of the participants were recorded. Results: There was a statistically significant positive correlation between the homeostatic model assessment of insulin resistance (HOMA-IR) and waist circumference/hip circumference ratio in the patient group (r=0.656, p<0.001). The mean luteinizing hormone (LH) levels of the patient group were found to be statistically significantly higher than the control group (p=0.048). The median FGS of the patient group was statistically significantly higher than the control group (p<0.001). Serum total testosterone levels of adolescent girls who have polycystic ovaries were statistically significantly higher than the ones who have not (p=0.001). The median FGS of those with polycystic ovarian appearance on ultrasonography was found to be statistically significantly higher than those without (p=0.034). Conclusion: Among the Rotterdam diagnostic criteria, oligoanovulation, acne, and polycystic ovarian appearance on ultrasonography can be seen in healthy adolescents without PCOS. In this study, the most supportive finding for the diagnosis of PCOS was the appearance of polycystic ovaries accompanying moderate hirsutism.https://dergipark.org.tr/en/download/article-file/2314640polycystic ovary syndromeadolescent girlsfree androgen indexhoma-irpolikistik over sendromuadölesan kızlarserbest androjen indeksihoma-ir |
| spellingShingle | Mustafa Harı Mehmet Burak Çimen Hüseyin Durukan Mahmut Bakır Koyuncu Ramazan Gen Polycystic Ovary Syndrome in Adolescent Period: Physical, Metabolic, and Hormonal Features Düzce Tıp Fakültesi Dergisi polycystic ovary syndrome adolescent girls free androgen index homa-ir polikistik over sendromu adölesan kızlar serbest androjen indeksi homa-ir |
| title | Polycystic Ovary Syndrome in Adolescent Period: Physical, Metabolic, and Hormonal Features |
| title_full | Polycystic Ovary Syndrome in Adolescent Period: Physical, Metabolic, and Hormonal Features |
| title_fullStr | Polycystic Ovary Syndrome in Adolescent Period: Physical, Metabolic, and Hormonal Features |
| title_full_unstemmed | Polycystic Ovary Syndrome in Adolescent Period: Physical, Metabolic, and Hormonal Features |
| title_short | Polycystic Ovary Syndrome in Adolescent Period: Physical, Metabolic, and Hormonal Features |
| title_sort | polycystic ovary syndrome in adolescent period physical metabolic and hormonal features |
| topic | polycystic ovary syndrome adolescent girls free androgen index homa-ir polikistik over sendromu adölesan kızlar serbest androjen indeksi homa-ir |
| url | https://dergipark.org.tr/en/download/article-file/2314640 |
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