ISOLATION AND PURIFICATION OF A KRINGLE 5 FROM HUMAN PLASMINOGEN USING AH-SEPHAROSE

ISOLATION AND PURIFICATION OF A KRINGLE 5 FROM HUMAN PLASMINOGEN USING AH-SEPHAROSE

Our aim was to develop a method for isolation of human plasminogen kringle 5 possessing functional activity. The proposed method includes the following steps: hydrolysis of plasminogen with elastase, separation of mini-plasminogen from kringle fragments 1–3 and 4 on Lys-Sepharose, mini-plasminogen h...

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Bibliographic Details
Main Authors: Kapustianenko L. G., Iatsenko T. A., Iusova O. I., Grinenko T. V.
Format: Article
Language:English
Published: National Academy of Sciences of Ukraine, Palladin Institute of Biochemistry 2014-08-01
Series:Biotechnologia Acta
Subjects:
plasminogen
fragments of plasminogen
kringle 5
angiostatins
Online Access:http://biotechnology.kiev.ua/images/storage/4_2014/kapustianenko.pdf

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