Chlorhexidine-filled porous ceramic coating fabricated by the aerosol deposition method for immediate and long-term enveloped virus inactivation

We developed an antiviral ceramic coating for immediate and long-term enveloped virus inactivation. The coating consisted of a porous ceramic coating fabricated by aerosol deposition and filled with chlorhexidine (CHX). The coating immediately inactivated enveloped viruses by releasing CHX. Furtherm...

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Main Authors: Taku Goto, Yoichi Yamada, Takeji Ueda, Sumiko Shiota, Mitsugu Sohma, Jun Akedo
Format: Article
Language:English
Published: Taylor & Francis Group 2022-04-01
Series:Journal of Asian Ceramic Societies
Subjects:
Online Access:https://www.tandfonline.com/doi/10.1080/21870764.2022.2072081
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author Taku Goto
Yoichi Yamada
Takeji Ueda
Sumiko Shiota
Mitsugu Sohma
Jun Akedo
author_facet Taku Goto
Yoichi Yamada
Takeji Ueda
Sumiko Shiota
Mitsugu Sohma
Jun Akedo
author_sort Taku Goto
collection DOAJ
description We developed an antiviral ceramic coating for immediate and long-term enveloped virus inactivation. The coating consisted of a porous ceramic coating fabricated by aerosol deposition and filled with chlorhexidine (CHX). The coating immediately inactivated enveloped viruses by releasing CHX. Furthermore, after the coating was repeatedly washed to simulate practical use, it still showed antiviral activity because CHX leakage was suppressed by the nanopores in the coating. We expect our antiviral coating to exhibit antiviral activity under conditions similar to practical use.
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spelling doaj.art-160296a44dbc461e80f5c4ff33ca58b92022-12-22T02:50:15ZengTaylor & Francis GroupJournal of Asian Ceramic Societies2187-07642022-04-0110246547210.1080/21870764.2022.2072081Chlorhexidine-filled porous ceramic coating fabricated by the aerosol deposition method for immediate and long-term enveloped virus inactivationTaku Goto0Yoichi Yamada1Takeji Ueda2Sumiko Shiota3Mitsugu Sohma4Jun Akedo5Advanced Coating Technology Research Center, National Institute of Advanced Industrial Science and Technology, Tsukuba, JapanSchool of Pharmacy, Shujitsu University, Okayama, JapanSchool of Pharmacy, Shujitsu University, Okayama, JapanSchool of Pharmacy, Shujitsu University, Okayama, JapanAdvanced Coating Technology Research Center, National Institute of Advanced Industrial Science and Technology, Tsukuba, JapanAdvanced Coating Technology Research Center, National Institute of Advanced Industrial Science and Technology, Tsukuba, JapanWe developed an antiviral ceramic coating for immediate and long-term enveloped virus inactivation. The coating consisted of a porous ceramic coating fabricated by aerosol deposition and filled with chlorhexidine (CHX). The coating immediately inactivated enveloped viruses by releasing CHX. Furthermore, after the coating was repeatedly washed to simulate practical use, it still showed antiviral activity because CHX leakage was suppressed by the nanopores in the coating. We expect our antiviral coating to exhibit antiviral activity under conditions similar to practical use.https://www.tandfonline.com/doi/10.1080/21870764.2022.2072081Porous ceramic coatingaerosol deposition methodanti-viral coating
spellingShingle Taku Goto
Yoichi Yamada
Takeji Ueda
Sumiko Shiota
Mitsugu Sohma
Jun Akedo
Chlorhexidine-filled porous ceramic coating fabricated by the aerosol deposition method for immediate and long-term enveloped virus inactivation
Journal of Asian Ceramic Societies
Porous ceramic coating
aerosol deposition method
anti-viral coating
title Chlorhexidine-filled porous ceramic coating fabricated by the aerosol deposition method for immediate and long-term enveloped virus inactivation
title_full Chlorhexidine-filled porous ceramic coating fabricated by the aerosol deposition method for immediate and long-term enveloped virus inactivation
title_fullStr Chlorhexidine-filled porous ceramic coating fabricated by the aerosol deposition method for immediate and long-term enveloped virus inactivation
title_full_unstemmed Chlorhexidine-filled porous ceramic coating fabricated by the aerosol deposition method for immediate and long-term enveloped virus inactivation
title_short Chlorhexidine-filled porous ceramic coating fabricated by the aerosol deposition method for immediate and long-term enveloped virus inactivation
title_sort chlorhexidine filled porous ceramic coating fabricated by the aerosol deposition method for immediate and long term enveloped virus inactivation
topic Porous ceramic coating
aerosol deposition method
anti-viral coating
url https://www.tandfonline.com/doi/10.1080/21870764.2022.2072081
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