Staphylococcus aureus delta toxin modulates both extracellular membrane vesicle biogenesis and amyloid formation

ABSTRACT Staphylococcus aureus secretes phenol-soluble modulins (PSMs), a family of small, amphipathic, secreted peptides with multiple biologic activities. Community-acquired S. aureus strains produce high levels of PSMs in planktonic cultures, and PSM alpha peptides have been shown to augment the...

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Bibliographic Details
Main Authors: Xiaogang Wang, Divakara SSM Uppu, Seth W. Dickey, Dylan J. Burgin, Michael Otto, Jean C. Lee
Format: Article
Language:English
Published: American Society for Microbiology 2023-10-01
Series:mBio
Subjects:
Online Access:https://journals.asm.org/doi/10.1128/mbio.01748-23