LINEA ALBA COLLAGEN ASSESSMENT IN MORBIDLY OBESE PATIENTS
ABSTRACT Background: The evaluation of collagen in the abdominal wall has been increasingly studied because of the relevance on collagen in the healing process after laparotomy. Aim: To evaluate the amount of collagen in the linea alba of patients undergoing laparotomic bariatric surgery and comp...
| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
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Colégio Brasileiro de Cirurgia Digestiva
2016-01-01
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| Series: | ABCD: Arquivos Brasileiros de Cirurgia Digestiva |
| Subjects: | |
| Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-67202016000600008&tlng=pt |
| _version_ | 1828127268374839296 |
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| author | João Vicente Machado GROSSI Felipe Fernandes NICOLA Ivan Alberto ZEPEDA Martina BECKER Eduardo Neubarth TRINDADE Vinicius Von DIEMEN Leandro Totti CAVAZZOLA Manoel Roberto Maciel TRINDADE |
| author_facet | João Vicente Machado GROSSI Felipe Fernandes NICOLA Ivan Alberto ZEPEDA Martina BECKER Eduardo Neubarth TRINDADE Vinicius Von DIEMEN Leandro Totti CAVAZZOLA Manoel Roberto Maciel TRINDADE |
| author_sort | João Vicente Machado GROSSI |
| collection | DOAJ |
| description | ABSTRACT Background: The evaluation of collagen in the abdominal wall has been increasingly studied because of the relevance on collagen in the healing process after laparotomy. Aim: To evaluate the amount of collagen in the linea alba of patients undergoing laparotomic bariatric surgery and comparing with non-obese cadavers. Methods: Were evaluated 88 samples of aponeurosis from abdominal linea alba of 44 obese patients (obesity group) and 44 non-obese cadavers (control group). The samples were collected in 2013 and 2104, and were sorted according to age (18-30, 31-45 and 46-60), gender, BMI, waist and cervical circumference, and subcutaneous tissue thickness. Material for biopsy was collected from the supraumbilical region of the linea alba for immunohistochemical analysis differentiating collagen type 1 and type 3 and the 1/3 ratio. Image-Pro Plus pixel counting software was used to measure the amount of collagen. Results: The obesity group evidenced mean age 44.11±9.90 years; 18-30 age group had three (6.8%) obese individuals; 31-45 had 22 (50%) and 46-60 had 19 (43.1%). Females were present in 81.8% (n=36); BMI (kg/m²) was 48.81±6.5; waist circumference (cm) was 136.761±13.55; subcutaneous tissue thickness (cm) 4.873±0.916. Considering age groups, gender and BMI, there were statistical differences in all tests when compared with the cadavers. Conclusion: The amount of collagen in the linea alba above the umbilical region in the morbidly obese patients was smaller than in the non-obese cadavers in the same age group. |
| first_indexed | 2024-04-11T15:47:38Z |
| format | Article |
| id | doaj.art-160a4e392c2f459dac6899649916245c |
| institution | Directory Open Access Journal |
| issn | 0102-6720 |
| language | English |
| last_indexed | 2024-04-11T15:47:38Z |
| publishDate | 2016-01-01 |
| publisher | Colégio Brasileiro de Cirurgia Digestiva |
| record_format | Article |
| series | ABCD: Arquivos Brasileiros de Cirurgia Digestiva |
| spelling | doaj.art-160a4e392c2f459dac6899649916245c2022-12-22T04:15:28ZengColégio Brasileiro de Cirurgia DigestivaABCD: Arquivos Brasileiros de Cirurgia Digestiva0102-67202016-01-0129suppl 181110.1590/0102-6720201600s10003LINEA ALBA COLLAGEN ASSESSMENT IN MORBIDLY OBESE PATIENTSJoão Vicente Machado GROSSIFelipe Fernandes NICOLAIvan Alberto ZEPEDAMartina BECKEREduardo Neubarth TRINDADEVinicius Von DIEMENLeandro Totti CAVAZZOLAManoel Roberto Maciel TRINDADEABSTRACT Background: The evaluation of collagen in the abdominal wall has been increasingly studied because of the relevance on collagen in the healing process after laparotomy. Aim: To evaluate the amount of collagen in the linea alba of patients undergoing laparotomic bariatric surgery and comparing with non-obese cadavers. Methods: Were evaluated 88 samples of aponeurosis from abdominal linea alba of 44 obese patients (obesity group) and 44 non-obese cadavers (control group). The samples were collected in 2013 and 2104, and were sorted according to age (18-30, 31-45 and 46-60), gender, BMI, waist and cervical circumference, and subcutaneous tissue thickness. Material for biopsy was collected from the supraumbilical region of the linea alba for immunohistochemical analysis differentiating collagen type 1 and type 3 and the 1/3 ratio. Image-Pro Plus pixel counting software was used to measure the amount of collagen. Results: The obesity group evidenced mean age 44.11±9.90 years; 18-30 age group had three (6.8%) obese individuals; 31-45 had 22 (50%) and 46-60 had 19 (43.1%). Females were present in 81.8% (n=36); BMI (kg/m²) was 48.81±6.5; waist circumference (cm) was 136.761±13.55; subcutaneous tissue thickness (cm) 4.873±0.916. Considering age groups, gender and BMI, there were statistical differences in all tests when compared with the cadavers. Conclusion: The amount of collagen in the linea alba above the umbilical region in the morbidly obese patients was smaller than in the non-obese cadavers in the same age group.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-67202016000600008&tlng=ptAnastomosis, Roux-en-YBariatric surgeryGastric bypassStenosis |
| spellingShingle | João Vicente Machado GROSSI Felipe Fernandes NICOLA Ivan Alberto ZEPEDA Martina BECKER Eduardo Neubarth TRINDADE Vinicius Von DIEMEN Leandro Totti CAVAZZOLA Manoel Roberto Maciel TRINDADE LINEA ALBA COLLAGEN ASSESSMENT IN MORBIDLY OBESE PATIENTS ABCD: Arquivos Brasileiros de Cirurgia Digestiva Anastomosis, Roux-en-Y Bariatric surgery Gastric bypass Stenosis |
| title | LINEA ALBA COLLAGEN ASSESSMENT IN MORBIDLY OBESE PATIENTS |
| title_full | LINEA ALBA COLLAGEN ASSESSMENT IN MORBIDLY OBESE PATIENTS |
| title_fullStr | LINEA ALBA COLLAGEN ASSESSMENT IN MORBIDLY OBESE PATIENTS |
| title_full_unstemmed | LINEA ALBA COLLAGEN ASSESSMENT IN MORBIDLY OBESE PATIENTS |
| title_short | LINEA ALBA COLLAGEN ASSESSMENT IN MORBIDLY OBESE PATIENTS |
| title_sort | linea alba collagen assessment in morbidly obese patients |
| topic | Anastomosis, Roux-en-Y Bariatric surgery Gastric bypass Stenosis |
| url | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-67202016000600008&tlng=pt |
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