An in vitro investigation of the effects of urolithins A and B on low-density lipoprotein uptake and its regulatory genes

An in vitro investigation of the effects of urolithins A and B on low-density lipoprotein uptake and its regulatory genes

Introduction This study aimed to evaluate the possible role of urolithin A (UA) and urolithin B (UB) on the mRNA expression levels of LDL receptor (LDLR) and PSCK9 genes, and also of the uptake of LDL particles in HepG2 cells. Material and methods The potential role of UA and UB on the induction of...

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Bibliographic Details
Main Authors: Shiva Ganjali, Maryam Matbou Riahi, Khadijeh Mahboobnia, Milad Iranshahy, Maciej Banach, Ali Jangjoo, Sorour Ashari, Zahra Tayarani-Najaran, Amirhossein Sahebkar
Format: Article
Language:English
Published: Termedia Publishing House 2023-06-01
Series:Archives of Medical Science
Subjects:
urolithin a
urolithin b
ldl receptor
ldl uptake
pcsk9
hepg2
Online Access:https://www.archivesofmedicalscience.com/An-in-vitro-investigation-of-the-effects-of-urolithins-A-and-B-on-low-density-lipoprotein,168120,0,2.html

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