THE PREVALENCE OF HERPES VIRUS INFECTIONS IN CHILDREN WITH HYPERTROPHY OF THE GLUTAL MINDALINE
Objective: to evaluate the clinical and epidemiological features of chronic adenoiditis and adenotonzillitis in children with nasopharyngeal carriage of the Epstein-Barr virus, cytomegalovirus and human herpesvirus 6. We conducted open comparative study, which involved 200 patients undergoing conser...
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| Format: | Article |
| Language: | Russian |
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Ltd. “The National Academy of Pediatric Science and Innovation”
2018-11-01
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| Series: | Rossijskij Vestnik Perinatologii i Pediatrii |
| Subjects: | |
| Online Access: | https://www.ped-perinatology.ru/jour/article/view/743 |
| _version_ | 1797875220776747008 |
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| author | S. V. Khaliullina V. A. Anokhin K. R. Khaliullina E. M. Pokrovskaya |
| author_facet | S. V. Khaliullina V. A. Anokhin K. R. Khaliullina E. M. Pokrovskaya |
| author_sort | S. V. Khaliullina |
| collection | DOAJ |
| description | Objective: to evaluate the clinical and epidemiological features of chronic adenoiditis and adenotonzillitis in children with nasopharyngeal carriage of the Epstein-Barr virus, cytomegalovirus and human herpesvirus 6. We conducted open comparative study, which involved 200 patients undergoing conservative and surgical treatment (adenotomy, adenotonzillotomy) at the ENT department of the Medical Center “Mart” (Kazan).Results. We obtained positive result of herpesvirus test in 65% (95% CI 58.4–71.6), 130/200 cases. There were registered 92 cases of the Epstein-Barr virus infection (70.8% [95% CI 63–78.6]), 46 – cytomegalovirus (35.4% [95% CI 27.2–43.6]) and 56 – human herpesvirus 6 (43.1% [95% CI 34.6–51.6]). 100% of patients with herpesvirus 6 had recurrent respiratory diseases, an increase in the cervical group of lymph nodes; 36.4% (95% CI 16.4–56.4%), 8/22 of these patients did not need operative treatment. Patients with the Epstein-Barr virus, cytomegalovirus and their combination more often complained of hypertrophy of the pharyngeal tonsil, recurrent otitis and a decrease in hearing, p<0.01. Patients with Epstein-Barr virus infection (11.9% [95% CI 2.2–21.6]), 5/42) were more often dissatisfied with the treatment results.Conclusion: effective options of treatment and prevention of hypertrophy of the lymphoid tissue of the pharyngeal ring should include etiotropic therapy of herpesvirus infections. |
| first_indexed | 2024-04-10T01:43:09Z |
| format | Article |
| id | doaj.art-16162ec399b349ce92aa294bef97b446 |
| institution | Directory Open Access Journal |
| issn | 1027-4065 2500-2228 |
| language | Russian |
| last_indexed | 2024-04-10T01:43:09Z |
| publishDate | 2018-11-01 |
| publisher | Ltd. “The National Academy of Pediatric Science and Innovation” |
| record_format | Article |
| series | Rossijskij Vestnik Perinatologii i Pediatrii |
| spelling | doaj.art-16162ec399b349ce92aa294bef97b4462023-03-13T09:12:45ZrusLtd. “The National Academy of Pediatric Science and Innovation”Rossijskij Vestnik Perinatologii i Pediatrii1027-40652500-22282018-11-0163516216610.21508/1027-4065-2018-63-5-162-166649THE PREVALENCE OF HERPES VIRUS INFECTIONS IN CHILDREN WITH HYPERTROPHY OF THE GLUTAL MINDALINES. V. Khaliullina0V. A. Anokhin1K. R. Khaliullina2E. M. Pokrovskaya3ФГБОУ ВО «Казанский государственный медицинский университет» Минздрава РФ; ГАУЗ «Республиканская клиническая инфекционная больница имени профессора А.Ф.Агафонова».ФГБОУ ВО «Казанский государственный медицинский университет» Минздрава РФ.ФГБОУ ВО «Казанский государственный медицинский университет» Минздрава РФ.Медицинская клиника «МАРТ».Objective: to evaluate the clinical and epidemiological features of chronic adenoiditis and adenotonzillitis in children with nasopharyngeal carriage of the Epstein-Barr virus, cytomegalovirus and human herpesvirus 6. We conducted open comparative study, which involved 200 patients undergoing conservative and surgical treatment (adenotomy, adenotonzillotomy) at the ENT department of the Medical Center “Mart” (Kazan).Results. We obtained positive result of herpesvirus test in 65% (95% CI 58.4–71.6), 130/200 cases. There were registered 92 cases of the Epstein-Barr virus infection (70.8% [95% CI 63–78.6]), 46 – cytomegalovirus (35.4% [95% CI 27.2–43.6]) and 56 – human herpesvirus 6 (43.1% [95% CI 34.6–51.6]). 100% of patients with herpesvirus 6 had recurrent respiratory diseases, an increase in the cervical group of lymph nodes; 36.4% (95% CI 16.4–56.4%), 8/22 of these patients did not need operative treatment. Patients with the Epstein-Barr virus, cytomegalovirus and their combination more often complained of hypertrophy of the pharyngeal tonsil, recurrent otitis and a decrease in hearing, p<0.01. Patients with Epstein-Barr virus infection (11.9% [95% CI 2.2–21.6]), 5/42) were more often dissatisfied with the treatment results.Conclusion: effective options of treatment and prevention of hypertrophy of the lymphoid tissue of the pharyngeal ring should include etiotropic therapy of herpesvirus infections.https://www.ped-perinatology.ru/jour/article/view/743детиаденоидыгипертрофия глоточной и небных миндалингерпесвирусыэпштейна–барр вирусцитомегаловирусвирус герпеса человека 6 типа |
| spellingShingle | S. V. Khaliullina V. A. Anokhin K. R. Khaliullina E. M. Pokrovskaya THE PREVALENCE OF HERPES VIRUS INFECTIONS IN CHILDREN WITH HYPERTROPHY OF THE GLUTAL MINDALINE Rossijskij Vestnik Perinatologii i Pediatrii дети аденоиды гипертрофия глоточной и небных миндалин герпесвирусы эпштейна–барр вирус цитомегаловирус вирус герпеса человека 6 типа |
| title | THE PREVALENCE OF HERPES VIRUS INFECTIONS IN CHILDREN WITH HYPERTROPHY OF THE GLUTAL MINDALINE |
| title_full | THE PREVALENCE OF HERPES VIRUS INFECTIONS IN CHILDREN WITH HYPERTROPHY OF THE GLUTAL MINDALINE |
| title_fullStr | THE PREVALENCE OF HERPES VIRUS INFECTIONS IN CHILDREN WITH HYPERTROPHY OF THE GLUTAL MINDALINE |
| title_full_unstemmed | THE PREVALENCE OF HERPES VIRUS INFECTIONS IN CHILDREN WITH HYPERTROPHY OF THE GLUTAL MINDALINE |
| title_short | THE PREVALENCE OF HERPES VIRUS INFECTIONS IN CHILDREN WITH HYPERTROPHY OF THE GLUTAL MINDALINE |
| title_sort | prevalence of herpes virus infections in children with hypertrophy of the glutal mindaline |
| topic | дети аденоиды гипертрофия глоточной и небных миндалин герпесвирусы эпштейна–барр вирус цитомегаловирус вирус герпеса человека 6 типа |
| url | https://www.ped-perinatology.ru/jour/article/view/743 |
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