Phage Engineering for Targeted Multidrug-Resistant <i>Escherichia coli</i>

Phage Engineering for Targeted Multidrug-Resistant <i>Escherichia coli</i>

The lytic bacteriophages have potential application value in the treatment of bacterial infections. However, the narrow host spectrum of these phages limits their range of clinical application. Here, we demonstrate the use of scarless Cas9-assisted recombination (no-SCAR) gene-editing technology to...

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Bibliographic Details
Main Authors: Jiaoyang Song, Zhengjie Liu, Qing Zhang, Yuqing Liu, Yibao Chen
Format: Article
Language:English
Published: MDPI AG 2023-01-01
Series:International Journal of Molecular Sciences
Subjects:
CRISPR/Cas9
engineering phage
phage tail fibers
multidrug resistant bacteria
Online Access:https://www.mdpi.com/1422-0067/24/3/2459

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