Research Progress of Milk-derived Blood Pressure-lowering Peptides

Hypertension is a "silent killer" that threatens human health. Milk-derived antihypertensive peptides with antihypertensive activity are prepared from milk protein by enzymatic hydrolysis or fermentation. Recent years, milk-derived antihypertensive peptides have been regarded as a natural...

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Main Authors: Shurou CHEN, Huagen XU, Jiali PAN, Jing LI, Xia LI, Tiemin JIANG, Xinhong DONG
Format: Article
Language:zho
Published: The editorial department of Science and Technology of Food Industry 2023-10-01
Series:Shipin gongye ke-ji
Subjects:
Online Access:http://www.spgykj.com/cn/article/doi/10.13386/j.issn1002-0306.2022090285
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author Shurou CHEN
Huagen XU
Jiali PAN
Jing LI
Xia LI
Tiemin JIANG
Xinhong DONG
author_facet Shurou CHEN
Huagen XU
Jiali PAN
Jing LI
Xia LI
Tiemin JIANG
Xinhong DONG
author_sort Shurou CHEN
collection DOAJ
description Hypertension is a "silent killer" that threatens human health. Milk-derived antihypertensive peptides with antihypertensive activity are prepared from milk protein by enzymatic hydrolysis or fermentation. Recent years, milk-derived antihypertensive peptides have been regarded as a natural and relatively safe bioactive peptide, which have attracted increasing attention due to their high biological activity, low toxicity, easy metabolism and good antihypertensive effect. And milk-derived antihypertensive peptides have been gradually applied to health care products, functional foods and other fields. In this paper, the research progress in the sources (chemically synthesized and natural food sources) and preparation methods (digestibility in vitro and microbial fermentation). This paper summarizes the separation and purification, and structure-activity relationship of milk-derived antihypertensive peptides is reviewed, and the future development prospects for food and clinical applications are outlined, which will provide reference for promoting the development of antihypertensive peptide products in China.
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spelling doaj.art-162161d895b44adc8b40fdac51df095f2023-10-11T09:18:38ZzhoThe editorial department of Science and Technology of Food IndustryShipin gongye ke-ji1002-03062023-10-01442042243010.13386/j.issn1002-0306.20220902852022090285-20Research Progress of Milk-derived Blood Pressure-lowering PeptidesShurou CHEN0Huagen XU1Jiali PAN2Jing LI3Xia LI4Tiemin JIANG5Xinhong DONG6College of Chemistry and Bioengineering, Guilin University of Technology, Guilin 541000, ChinaCollege of Chemistry and Bioengineering, Guilin University of Technology, Guilin 541000, ChinaCollege of Chemistry and Bioengineering, Guilin University of Technology, Guilin 541000, ChinaCollege of Chemistry and Bioengineering, Guilin University of Technology, Guilin 541000, ChinaCollege of Chemistry and Bioengineering, Guilin University of Technology, Guilin 541000, ChinaCollege of Chemistry and Bioengineering, Guilin University of Technology, Guilin 541000, ChinaCollege of Chemistry and Bioengineering, Guilin University of Technology, Guilin 541000, ChinaHypertension is a "silent killer" that threatens human health. Milk-derived antihypertensive peptides with antihypertensive activity are prepared from milk protein by enzymatic hydrolysis or fermentation. Recent years, milk-derived antihypertensive peptides have been regarded as a natural and relatively safe bioactive peptide, which have attracted increasing attention due to their high biological activity, low toxicity, easy metabolism and good antihypertensive effect. And milk-derived antihypertensive peptides have been gradually applied to health care products, functional foods and other fields. In this paper, the research progress in the sources (chemically synthesized and natural food sources) and preparation methods (digestibility in vitro and microbial fermentation). This paper summarizes the separation and purification, and structure-activity relationship of milk-derived antihypertensive peptides is reviewed, and the future development prospects for food and clinical applications are outlined, which will provide reference for promoting the development of antihypertensive peptide products in China.http://www.spgykj.com/cn/article/doi/10.13386/j.issn1002-0306.2022090285antihypertensive peptidespreparation methodisolation and purificationstructure-activity relationshipblood pressure lowering effect study
spellingShingle Shurou CHEN
Huagen XU
Jiali PAN
Jing LI
Xia LI
Tiemin JIANG
Xinhong DONG
Research Progress of Milk-derived Blood Pressure-lowering Peptides
Shipin gongye ke-ji
antihypertensive peptides
preparation method
isolation and purification
structure-activity relationship
blood pressure lowering effect study
title Research Progress of Milk-derived Blood Pressure-lowering Peptides
title_full Research Progress of Milk-derived Blood Pressure-lowering Peptides
title_fullStr Research Progress of Milk-derived Blood Pressure-lowering Peptides
title_full_unstemmed Research Progress of Milk-derived Blood Pressure-lowering Peptides
title_short Research Progress of Milk-derived Blood Pressure-lowering Peptides
title_sort research progress of milk derived blood pressure lowering peptides
topic antihypertensive peptides
preparation method
isolation and purification
structure-activity relationship
blood pressure lowering effect study
url http://www.spgykj.com/cn/article/doi/10.13386/j.issn1002-0306.2022090285
work_keys_str_mv AT shurouchen researchprogressofmilkderivedbloodpressureloweringpeptides
AT huagenxu researchprogressofmilkderivedbloodpressureloweringpeptides
AT jialipan researchprogressofmilkderivedbloodpressureloweringpeptides
AT jingli researchprogressofmilkderivedbloodpressureloweringpeptides
AT xiali researchprogressofmilkderivedbloodpressureloweringpeptides
AT tieminjiang researchprogressofmilkderivedbloodpressureloweringpeptides
AT xinhongdong researchprogressofmilkderivedbloodpressureloweringpeptides