Neurodegenerative diseases and blood pressure variability: A comprehensive review from HOPE Asia

Abstract Asia has an enormous number of older people and is the primary contributor to the rise in neurodegenerative diseases such as Alzheimer's and Parkinson's disease. The therapy of many neurodegenerative diseases has not yet progressed to the point where it is possible to alter the co...

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Main Authors: Yuda Turana, Robert Shen, Michael Nathaniel, Yook‐Chin Chia, Yan Li, Kazuomi Kario
Format: Article
Language:English
Published: Wiley 2022-09-01
Series:The Journal of Clinical Hypertension
Subjects:
Online Access:https://doi.org/10.1111/jch.14559
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author Yuda Turana
Robert Shen
Michael Nathaniel
Yook‐Chin Chia
Yan Li
Kazuomi Kario
author_facet Yuda Turana
Robert Shen
Michael Nathaniel
Yook‐Chin Chia
Yan Li
Kazuomi Kario
author_sort Yuda Turana
collection DOAJ
description Abstract Asia has an enormous number of older people and is the primary contributor to the rise in neurodegenerative diseases such as Alzheimer's and Parkinson's disease. The therapy of many neurodegenerative diseases has not yet progressed to the point where it is possible to alter the course of the disease. Mid‐life hypertension is an important predictor of later‐life cognitive impairment and brain neurodegenerative conditions. These findings highlight the pivotal role of preventing and managing hypertension as a risk factor for neurodegenerative disease. Autonomic dysfunction, neuropsychiatric and sleep disturbances can arise in neurodegenerative diseases, resulting in blood pressure variability (BPV). The BPV itself can worsen the progression of the disease. In older people with neurodegenerative disease and hypertension, it is critical to consider 24‐h blood pressure monitoring and personalized blood pressure therapy.
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spelling doaj.art-162aed1994634ab79ed14d9fdc9d56942023-10-30T13:26:45ZengWileyThe Journal of Clinical Hypertension1524-61751751-71762022-09-012491204121710.1111/jch.14559Neurodegenerative diseases and blood pressure variability: A comprehensive review from HOPE AsiaYuda Turana0Robert Shen1Michael Nathaniel2Yook‐Chin Chia3Yan Li4Kazuomi Kario5School of Medicine and Health Sciences Atma Jaya Catholic University of Indonesia North Jakarta Jakarta IndonesiaSchool of Medicine and Health Sciences Atma Jaya Catholic University of Indonesia North Jakarta Jakarta IndonesiaSchool of Medicine and Health Sciences Atma Jaya Catholic University of Indonesia North Jakarta Jakarta IndonesiaDepartment of Medical Sciences School of Medical and Life Sciences Sunway University Bandar Sunway MalaysiaDepartment of Cardiovascular Medicine Shanghai Key Lab of Hypertension Shanghai Institute of Hypertension National Research Centre for Translational Medicine Ruijin Hospital Shanghai Jiaotong University School of Medicine Shanghai ChinaDivision of Cardiovascular Medicine Department of Medicine Jichi Medical University School of Medicine Tochigi JapanAbstract Asia has an enormous number of older people and is the primary contributor to the rise in neurodegenerative diseases such as Alzheimer's and Parkinson's disease. The therapy of many neurodegenerative diseases has not yet progressed to the point where it is possible to alter the course of the disease. Mid‐life hypertension is an important predictor of later‐life cognitive impairment and brain neurodegenerative conditions. These findings highlight the pivotal role of preventing and managing hypertension as a risk factor for neurodegenerative disease. Autonomic dysfunction, neuropsychiatric and sleep disturbances can arise in neurodegenerative diseases, resulting in blood pressure variability (BPV). The BPV itself can worsen the progression of the disease. In older people with neurodegenerative disease and hypertension, it is critical to consider 24‐h blood pressure monitoring and personalized blood pressure therapy.https://doi.org/10.1111/jch.14559Alzheimer's diseasehypertensionneurodegenerativeParkinson
spellingShingle Yuda Turana
Robert Shen
Michael Nathaniel
Yook‐Chin Chia
Yan Li
Kazuomi Kario
Neurodegenerative diseases and blood pressure variability: A comprehensive review from HOPE Asia
The Journal of Clinical Hypertension
Alzheimer's disease
hypertension
neurodegenerative
Parkinson
title Neurodegenerative diseases and blood pressure variability: A comprehensive review from HOPE Asia
title_full Neurodegenerative diseases and blood pressure variability: A comprehensive review from HOPE Asia
title_fullStr Neurodegenerative diseases and blood pressure variability: A comprehensive review from HOPE Asia
title_full_unstemmed Neurodegenerative diseases and blood pressure variability: A comprehensive review from HOPE Asia
title_short Neurodegenerative diseases and blood pressure variability: A comprehensive review from HOPE Asia
title_sort neurodegenerative diseases and blood pressure variability a comprehensive review from hope asia
topic Alzheimer's disease
hypertension
neurodegenerative
Parkinson
url https://doi.org/10.1111/jch.14559
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AT michaelnathaniel neurodegenerativediseasesandbloodpressurevariabilityacomprehensivereviewfromhopeasia
AT yookchinchia neurodegenerativediseasesandbloodpressurevariabilityacomprehensivereviewfromhopeasia
AT yanli neurodegenerativediseasesandbloodpressurevariabilityacomprehensivereviewfromhopeasia
AT kazuomikario neurodegenerativediseasesandbloodpressurevariabilityacomprehensivereviewfromhopeasia