Inflammation and Negative Symptoms of Schizophrenia: Implications for Reward Processing and Motivational Deficits

Inflammation and Negative Symptoms of Schizophrenia: Implications for Reward Processing and Motivational Deficits

Negative symptoms of schizophrenia are debilitating and chronic in nature, are difficult to treat, and contribute to poor functional outcomes. Motivational deficits are a core negative symptom and may involve alterations in reward processing, which involve subcortical regions such as the basal gangl...

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Bibliographic Details
Main Authors: David R. Goldsmith, Mark Hyman Rapaport
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-02-01
Series:Frontiers in Psychiatry
Subjects:
inflammation
cytokines
negative symptoms
reward
motivation
schizophrenia
Online Access:https://www.frontiersin.org/article/10.3389/fpsyt.2020.00046/full

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