Mitochondrial Dysfunction and Stress Responses in Alzheimer’s Disease

Mitochondrial Dysfunction and Stress Responses in Alzheimer’s Disease

Alzheimer’s disease (AD) patients display widespread mitochondrial defects. Brain hypometabolism occurs alongside mitochondrial defects, and correlates well with cognitive decline. Numerous theories attempt to explain AD mitochondrial dysfunction. Groups propose AD mitochondrial defects st...

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Bibliographic Details
Main Authors:	Ian Weidling, Russell H. Swerdlow
Format:	Article
Language:	English
Published:	MDPI AG 2019-05-01
Series:	Biology
Subjects:	Alzheimer’s disease eIF2α metabolism mitochondria proteostasis stress response
Online Access:	https://www.mdpi.com/2079-7737/8/2/39

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