Intratumoural expression of IL-6/STAT3, IL-17 and FOXP3 immune cells in the immunosuppressive tumour microenvironment of colorectal cancer Immune cells-positive for IL-6, STAT3, IL-17 and FOXP3 and colorectal cancer development

Intratumoural expression of IL-6/STAT3, IL-17 and FOXP3 immune cells in the immunosuppressive tumour microenvironment of colorectal cancer Immune cells-positive for IL-6, STAT3, IL-17 and FOXP3 and colorectal cancer development

AbstractImmune cells in the tumour microenvironment (TME) interact with each other and with tumour cells to promote tumour development. IL-6/STAT3 pathway induces and maintains mainly pro-tumour TME. Macrophages and lymphocytes are positive for IL-6, STAT3 and IL-17, while FoxP3 cells are mainly reg...

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Bibliographic Details
Main Authors: Maya Vladova Gulubova, Dimitur Chavdarov Chonov, Koni Vancho Ivanova, Mariyna Kostova Hristova, Maria Magdalena Krasimirova-Ignatova, Tatyana Ivanova Vlaykova
Format: Article
Language:English
Published: Taylor & Francis Group 2022-12-01
Series:Biotechnology & Biotechnological Equipment
Subjects:
IL-6
IL-17
FoxP3
STAT3
colorectal cancer
Online Access:https://www.tandfonline.com/doi/10.1080/13102818.2022.2072765

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