Rectal tumor recurrence: What more may we learn?

Background: Notwithstanding real progress in the treatment of rectal cancers, local recurrence remains a challenging problem. We performed a retrospective observational study focusing on anatomo-surgical data. Methods: In our retrospective study, we adopted new morphological classifications of prima...

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Main Authors: Antonio Manenti, Massimiliano Salati, Alberto Farinetti, Maurizio Zizzo, Emilio Simonini
Format: Article
Language:English
Published: GESDAV 2017-09-01
Series:Archives of Clinical and Experimental Surgery
Subjects:
Online Access:http://www.ejmanager.com/fulltextpdf.php?mno=230168
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author Antonio Manenti
Massimiliano Salati
Alberto Farinetti
Maurizio Zizzo
Emilio Simonini
author_facet Antonio Manenti
Massimiliano Salati
Alberto Farinetti
Maurizio Zizzo
Emilio Simonini
author_sort Antonio Manenti
collection DOAJ
description Background: Notwithstanding real progress in the treatment of rectal cancers, local recurrence remains a challenging problem. We performed a retrospective observational study focusing on anatomo-surgical data. Methods: In our retrospective study, we adopted new morphological classifications of primary tumor downstaging, after neoadjuvant treatment, and of local recurrence of rectal cancers, mainly based on CT and MRI images. Results: Different risk factors of rectal cancer recurrence were identified: its initial advanced stage, its high histological grading, and its non-responsiveness to neoadjuvant treatment. In addition, particular anatomo-surgical points have been underlined, mainly focused on the total mesorectal excision. Conclusions: We reaffirmed the value of a correct surgical technique, although other aspects of this disease demand further research. [Arch Clin Exp Surg 2017; 6(3.000): 132-137]
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spelling doaj.art-1633d9a3e399401b9c1abee93cc3c72d2023-02-15T16:13:40ZengGESDAVArchives of Clinical and Experimental Surgery2146-81332017-09-016313213710.5455/aces.20160816012602230168Rectal tumor recurrence: What more may we learn?Antonio Manenti0Massimiliano Salati1Alberto Farinetti2Maurizio Zizzo3Emilio Simonini4Department of Surgery, University of Modena, Italy Department of Oncology, University of Modena, Italy Department of Surgery, University of Modena, Italy Department of Surgery, University of Modena, Italy Department of Radiology, University of Modena, ItalyBackground: Notwithstanding real progress in the treatment of rectal cancers, local recurrence remains a challenging problem. We performed a retrospective observational study focusing on anatomo-surgical data. Methods: In our retrospective study, we adopted new morphological classifications of primary tumor downstaging, after neoadjuvant treatment, and of local recurrence of rectal cancers, mainly based on CT and MRI images. Results: Different risk factors of rectal cancer recurrence were identified: its initial advanced stage, its high histological grading, and its non-responsiveness to neoadjuvant treatment. In addition, particular anatomo-surgical points have been underlined, mainly focused on the total mesorectal excision. Conclusions: We reaffirmed the value of a correct surgical technique, although other aspects of this disease demand further research. [Arch Clin Exp Surg 2017; 6(3.000): 132-137]http://www.ejmanager.com/fulltextpdf.php?mno=230168Rectal cancerrecurrentcomputed tomographymesorectal excisionneoadjuvant radio-chemotherapy
spellingShingle Antonio Manenti
Massimiliano Salati
Alberto Farinetti
Maurizio Zizzo
Emilio Simonini
Rectal tumor recurrence: What more may we learn?
Archives of Clinical and Experimental Surgery
Rectal cancer
recurrent
computed tomography
mesorectal excision
neoadjuvant radio-chemotherapy
title Rectal tumor recurrence: What more may we learn?
title_full Rectal tumor recurrence: What more may we learn?
title_fullStr Rectal tumor recurrence: What more may we learn?
title_full_unstemmed Rectal tumor recurrence: What more may we learn?
title_short Rectal tumor recurrence: What more may we learn?
title_sort rectal tumor recurrence what more may we learn
topic Rectal cancer
recurrent
computed tomography
mesorectal excision
neoadjuvant radio-chemotherapy
url http://www.ejmanager.com/fulltextpdf.php?mno=230168
work_keys_str_mv AT antoniomanenti rectaltumorrecurrencewhatmoremaywelearn
AT massimilianosalati rectaltumorrecurrencewhatmoremaywelearn
AT albertofarinetti rectaltumorrecurrencewhatmoremaywelearn
AT mauriziozizzo rectaltumorrecurrencewhatmoremaywelearn
AT emiliosimonini rectaltumorrecurrencewhatmoremaywelearn