Enhancing dissolution of artesunate from immediate release tablets using a green granulation technique

Enhancing dissolution of artesunate from immediate release tablets using a green granulation technique

Artesunate is a poorly soluble drug and liable to aqueous hydrolysis. This study aims to formulate Artesunate as an immediate release tablet through optimization of the melt granulation technique to improve the dissolution of the drug. Three different meltable binders were used (Polyethylene Glycol...

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Bibliographic Details
Main Authors: Akram ahmad Bashir, sameh abd-elhamid, Alia Badawi, Ahmed S. Geneidi
Format: Article
Language:English
Published: Ain Shams University 2019-06-01
Series:Archives of Pharmaceutical Sciences Ain Shams University
Subjects:
pore-forming
crystalline
Box-Behnken design
hot melt granulation
Modeling
Dissolution
Online Access:https://aps.journals.ekb.eg/article_29018.html

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