Engineered skeletal muscle recapitulates human muscle development, regeneration and dystrophy

Engineered skeletal muscle recapitulates human muscle development, regeneration and dystrophy

Abstract Background Human pluripotent stem cell‐derived muscle models show great potential for translational research. Here, we describe developmentally inspired methods for the derivation of skeletal muscle cells and their utility in skeletal muscle tissue engineering with the aim to model skeletal...

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Bibliographic Details
Main Authors: Mina Shahriyari, Md Rezaul Islam, Sadman M. Sakib, Malte Rinn, Anastasia Rika, Dennis Krüger, Lalit Kaurani, Verena Gisa, Mandy Winterhoff, Harithaa Anandakumar, Orr Shomroni, Matthias Schmidt, Gabriela Salinas, Andreas Unger, Wolfgang A. Linke, Jana Zschüntzsch, Jens Schmidt, Rhonda Bassel‐Duby, Eric N. Olson, André Fischer, Wolfram‐Hubertus Zimmermann, Malte Tiburcy
Format: Article
Language:English
Published: Wiley 2022-12-01
Series:Journal of Cachexia, Sarcopenia and Muscle
Subjects:
Duchenne muscular dystrophy
hypaxial dermomyotome
limb muscle
satellite cells
skeletal muscle organoid
somite
Online Access:https://doi.org/10.1002/jcsm.13094

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