Lipoarabinomannan in Active and Passive Protection Against Tuberculosis

Lipoarabinomannan in Active and Passive Protection Against Tuberculosis

Glycolipids of the cell wall of Mycobacterium tuberculosis (Mtb) are important immunomodulators in tuberculosis. In particular, lipoarabinomannan (LAM) has a profound effect on the innate immune response. LAM and its structural variants can be recognized by and activate human CD1b-restricted T cells...

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Bibliographic Details
Main Authors: Margarida Correia-Neves, Christopher Sundling, Andrea Cooper, Gunilla Källenius
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-09-01
Series:Frontiers in Immunology
Subjects:
lipoarabinomannan
tuberculosis
Mycobacterium
glycolipid
antibodies
monoclonal
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2019.01968/full

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