Francisella tularensis Outer Membrane Vesicles Participate in the Early Phase of Interaction With Macrophages

Francisella tularensis Outer Membrane Vesicles Participate in the Early Phase of Interaction With Macrophages

Francisella tularensis is known to release unusually shaped tubular outer membrane vesicles (OMV) containing a number of previously identified virulence factors and immunomodulatory proteins. In this study, we present that OMV isolated from the F. tularensis subsp. holarctica strain FSC200 enter rea...

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Bibliographic Details
Main Authors: Ivona Pavkova, Jana Klimentova, Jan Bavlovic, Lenka Horcickova, Klara Kubelkova, Erik Vlcak, Helena Raabova, Vlada Filimonenko, Ondrej Ballek, Jiri Stulik
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-10-01
Series:Frontiers in Microbiology
Subjects:
Francisella tularensis
FSC200
outer membrane vesicles
host–pathogen interaction
macrophage
cell entry
Online Access:https://www.frontiersin.org/articles/10.3389/fmicb.2021.748706/full

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