Histone malonylation is regulated by SIRT5 and KAT2A

Histone malonylation is regulated by SIRT5 and KAT2A

Summary: The posttranslational modification lysine malonylation is found in many proteins, including histones. However, it remains unclear whether histone malonylation is regulated or functionally relevant. Here, we report that availability of malonyl-co-enzyme A (malonyl-CoA), an endogenous malonyl...

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Détails bibliographiques
Auteurs principaux: Ran Zhang, Joanna Bons, Grace Scheidemantle, Xiaojing Liu, Olga Bielska, Chris Carrico, Jacob Rose, Indra Heckenbach, Morten Scheibye-Knudsen, Birgit Schilling, Eric Verdin
Format: Article
Langue:English
Publié: Elsevier 2023-03-01
Collection:iScience
Sujets:
Biological sciences
Molecular biology
Omics
Proteomics
Accès en ligne:http://www.sciencedirect.com/science/article/pii/S2589004223002705

Internet

http://www.sciencedirect.com/science/article/pii/S2589004223002705

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