Histone malonylation is regulated by SIRT5 and KAT2A

Summary: The posttranslational modification lysine malonylation is found in many proteins, including histones. However, it remains unclear whether histone malonylation is regulated or functionally relevant. Here, we report that availability of malonyl-co-enzyme A (malonyl-CoA), an endogenous malonyl...

תיאור מלא

מידע ביבליוגרפי
Main Authors: Ran Zhang, Joanna Bons, Grace Scheidemantle, Xiaojing Liu, Olga Bielska, Chris Carrico, Jacob Rose, Indra Heckenbach, Morten Scheibye-Knudsen, Birgit Schilling, Eric Verdin
פורמט: Article
שפה:English
יצא לאור: Elsevier 2023-03-01
סדרה:iScience
נושאים:
גישה מקוונת:http://www.sciencedirect.com/science/article/pii/S2589004223002705