Histone malonylation is regulated by SIRT5 and KAT2A

Histone malonylation is regulated by SIRT5 and KAT2A

Summary: The posttranslational modification lysine malonylation is found in many proteins, including histones. However, it remains unclear whether histone malonylation is regulated or functionally relevant. Here, we report that availability of malonyl-co-enzyme A (malonyl-CoA), an endogenous malonyl...

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Bibliographische Detailangaben
Hauptverfasser: Ran Zhang, Joanna Bons, Grace Scheidemantle, Xiaojing Liu, Olga Bielska, Chris Carrico, Jacob Rose, Indra Heckenbach, Morten Scheibye-Knudsen, Birgit Schilling, Eric Verdin
Format: Artikel
Sprache:English
Veröffentlicht: Elsevier 2023-03-01
Schriftenreihe:iScience
Schlagworte:
Biological sciences
Molecular biology
Omics
Proteomics
Online Zugang:http://www.sciencedirect.com/science/article/pii/S2589004223002705

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