Histone malonylation is regulated by SIRT5 and KAT2A

Histone malonylation is regulated by SIRT5 and KAT2A

Summary: The posttranslational modification lysine malonylation is found in many proteins, including histones. However, it remains unclear whether histone malonylation is regulated or functionally relevant. Here, we report that availability of malonyl-co-enzyme A (malonyl-CoA), an endogenous malonyl...

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Detalles Bibliográficos
Autores principales: Ran Zhang, Joanna Bons, Grace Scheidemantle, Xiaojing Liu, Olga Bielska, Chris Carrico, Jacob Rose, Indra Heckenbach, Morten Scheibye-Knudsen, Birgit Schilling, Eric Verdin
Formato: Artículo
Lenguaje:English
Publicado: Elsevier 2023-03-01
Colección:iScience
Materias:
Biological sciences
Molecular biology
Omics
Proteomics
Acceso en línea:http://www.sciencedirect.com/science/article/pii/S2589004223002705

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