Histone malonylation is regulated by SIRT5 and KAT2A
Summary: The posttranslational modification lysine malonylation is found in many proteins, including histones. However, it remains unclear whether histone malonylation is regulated or functionally relevant. Here, we report that availability of malonyl-co-enzyme A (malonyl-CoA), an endogenous malonyl...
Main Authors: | Ran Zhang, Joanna Bons, Grace Scheidemantle, Xiaojing Liu, Olga Bielska, Chris Carrico, Jacob Rose, Indra Heckenbach, Morten Scheibye-Knudsen, Birgit Schilling, Eric Verdin |
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Formato: | Artigo |
Idioma: | English |
Publicado em: |
Elsevier
2023-03-01
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Colecção: | iScience |
Assuntos: | |
Acesso em linha: | http://www.sciencedirect.com/science/article/pii/S2589004223002705 |
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