Histone malonylation is regulated by SIRT5 and KAT2A
Summary: The posttranslational modification lysine malonylation is found in many proteins, including histones. However, it remains unclear whether histone malonylation is regulated or functionally relevant. Here, we report that availability of malonyl-co-enzyme A (malonyl-CoA), an endogenous malonyl...
Principais autores: | Ran Zhang, Joanna Bons, Grace Scheidemantle, Xiaojing Liu, Olga Bielska, Chris Carrico, Jacob Rose, Indra Heckenbach, Morten Scheibye-Knudsen, Birgit Schilling, Eric Verdin |
---|---|
Formato: | Artigo |
Idioma: | English |
Publicado em: |
Elsevier
2023-03-01
|
coleção: | iScience |
Assuntos: | |
Acesso em linha: | http://www.sciencedirect.com/science/article/pii/S2589004223002705 |
Registros relacionados
-
Protocol for mass spectrometric profiling of lysine malonylation by lysine acetyltransferase in CRISPRi K562 cell lines
por: Ran Zhang, et al.
Publicado em: (2024-06-01) -
A novel splice variant of Elp3/Kat9 regulates mitochondrial tRNA modification and function
por: Rachid Boutoual, et al.
Publicado em: (2022-08-01) -
17-DMAG dually inhibits Hsp90 and histone lysine demethylases in alveolar rhabdomyosarcoma
por: Shivendra Singh, et al.
Publicado em: (2021-01-01) -
Polyadenylation of Histone H3.1 mRNA Promotes Cell Transformation by Displacing H3.3 from Gene Regulatory Elements
por: Danqi Chen, et al.
Publicado em: (2020-09-01) -
Real-time monitoring of deformed wing virus-infected bee foraging behavior following histone deacetylase inhibitor treatment
por: Cheng-Kang Tang, et al.
Publicado em: (2021-10-01)