Histone malonylation is regulated by SIRT5 and KAT2A

Summary: The posttranslational modification lysine malonylation is found in many proteins, including histones. However, it remains unclear whether histone malonylation is regulated or functionally relevant. Here, we report that availability of malonyl-co-enzyme A (malonyl-CoA), an endogenous malonyl...

詳細記述

書誌詳細
主要な著者: Ran Zhang, Joanna Bons, Grace Scheidemantle, Xiaojing Liu, Olga Bielska, Chris Carrico, Jacob Rose, Indra Heckenbach, Morten Scheibye-Knudsen, Birgit Schilling, Eric Verdin
フォーマット: 論文
言語:English
出版事項: Elsevier 2023-03-01
シリーズ:iScience
主題:
オンライン・アクセス:http://www.sciencedirect.com/science/article/pii/S2589004223002705