Results of Detecting SARS-CoV-2 and Other Pathogens of Community-Acquired Pneumonia by PCR in the Tyumen Region

The aim of this work was to identify the causative agent of community-acquired pneumonia and coinfection using PCR study of biomaterial from patients.Materials and methods. PCR testing of 268 samples from 258 patients was carried out to identify RNA/DNA of viral and bacterial pathogens of respirator...

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Main Authors: I. V. Bakshtanovskaya, T. F. Stepanova, G. V. Sharukho, A. N. Letyushev, K. B. Stepanova, N. V. Loginova, Ts. A. Panina, E. A. Zmatrakova, A. N. Kosyreva, A. Z. Bartusevich, S. A. Leont’eva, A. O. Vishnyakova
Format: Article
Language:Russian
Published: Federal Government Health Institution, Russian Research Anti-Plague Institute “Microbe” 2020-10-01
Series:Проблемы особо опасных инфекций
Subjects:
Online Access:https://journal.microbe.ru/jour/article/view/1375
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author I. V. Bakshtanovskaya
T. F. Stepanova
G. V. Sharukho
A. N. Letyushev
K. B. Stepanova
N. V. Loginova
Ts. A. Panina
E. A. Zmatrakova
A. N. Kosyreva
A. Z. Bartusevich
S. A. Leont’eva
A. O. Vishnyakova
author_facet I. V. Bakshtanovskaya
T. F. Stepanova
G. V. Sharukho
A. N. Letyushev
K. B. Stepanova
N. V. Loginova
Ts. A. Panina
E. A. Zmatrakova
A. N. Kosyreva
A. Z. Bartusevich
S. A. Leont’eva
A. O. Vishnyakova
author_sort I. V. Bakshtanovskaya
collection DOAJ
description The aim of this work was to identify the causative agent of community-acquired pneumonia and coinfection using PCR study of biomaterial from patients.Materials and methods. PCR testing of 268 samples from 258 patients was carried out to identify RNA/DNA of viral and bacterial pathogens of respiratory infections.Results and discussion. In 43.3 % of samples SARS-CoV-2 RNA was detected, in 4.5 % – RNA/DNA of acute respiratory viral infections pathogens, in one sample – DNA of Mycoplasma pneumoniae. Co-infection was detected only in patients of the anti-tuberculosis dispensary (SARS-CoV-2 and Mycobacterium tuberculosis). In the examined patients with pneumonia, SARS-CoV-2 RNA was significantly more often detected in biomaterial from the lower respiratory tract (52 %) than in respiratory smears (8.5 %). In the first week from the onset of the disease, 19.2 % of positive samples were found, in the second – 56.5 %.
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spelling doaj.art-1640517323bd4302a9172df145a35e9a2024-04-05T16:47:15ZrusFederal Government Health Institution, Russian Research Anti-Plague Institute “Microbe”Проблемы особо опасных инфекций0370-10692658-719X2020-10-010314614910.21055/0370-1069-2020-3-146-1491233Results of Detecting SARS-CoV-2 and Other Pathogens of Community-Acquired Pneumonia by PCR in the Tyumen RegionI. V. Bakshtanovskaya0T. F. Stepanova1G. V. Sharukho2A. N. Letyushev3K. B. Stepanova4N. V. Loginova5Ts. A. Panina6E. A. Zmatrakova7A. N. Kosyreva8A. Z. Bartusevich9S. A. Leont’eva10A. O. Vishnyakova11Tyumen Research Institute of the Regional Infection PathologyTyumen Research Institute of the Regional Infection PathologyRospotrebnadzor Administration in the Tyumen RegionTyumen Research Institute of the Regional Infection Pathology; Rospotrebnadzor Administration in the Tyumen RegionTyumen Research Institute of the Regional Infection PathologyDepartment of Health of the Tyumen RegionTyumen Research Institute of the Regional Infection PathologyTyumen Research Institute of the Regional Infection PathologyTyumen Research Institute of the Regional Infection PathologyTyumen Research Institute of the Regional Infection PathologyTyumen Research Institute of the Regional Infection PathologyTyumen Research Institute of the Regional Infection PathologyThe aim of this work was to identify the causative agent of community-acquired pneumonia and coinfection using PCR study of biomaterial from patients.Materials and methods. PCR testing of 268 samples from 258 patients was carried out to identify RNA/DNA of viral and bacterial pathogens of respiratory infections.Results and discussion. In 43.3 % of samples SARS-CoV-2 RNA was detected, in 4.5 % – RNA/DNA of acute respiratory viral infections pathogens, in one sample – DNA of Mycoplasma pneumoniae. Co-infection was detected only in patients of the anti-tuberculosis dispensary (SARS-CoV-2 and Mycobacterium tuberculosis). In the examined patients with pneumonia, SARS-CoV-2 RNA was significantly more often detected in biomaterial from the lower respiratory tract (52 %) than in respiratory smears (8.5 %). In the first week from the onset of the disease, 19.2 % of positive samples were found, in the second – 56.5 %.https://journal.microbe.ru/jour/article/view/1375pneumoniapcrsars-cov-2co-infections
spellingShingle I. V. Bakshtanovskaya
T. F. Stepanova
G. V. Sharukho
A. N. Letyushev
K. B. Stepanova
N. V. Loginova
Ts. A. Panina
E. A. Zmatrakova
A. N. Kosyreva
A. Z. Bartusevich
S. A. Leont’eva
A. O. Vishnyakova
Results of Detecting SARS-CoV-2 and Other Pathogens of Community-Acquired Pneumonia by PCR in the Tyumen Region
Проблемы особо опасных инфекций
pneumonia
pcr
sars-cov-2
co-infections
title Results of Detecting SARS-CoV-2 and Other Pathogens of Community-Acquired Pneumonia by PCR in the Tyumen Region
title_full Results of Detecting SARS-CoV-2 and Other Pathogens of Community-Acquired Pneumonia by PCR in the Tyumen Region
title_fullStr Results of Detecting SARS-CoV-2 and Other Pathogens of Community-Acquired Pneumonia by PCR in the Tyumen Region
title_full_unstemmed Results of Detecting SARS-CoV-2 and Other Pathogens of Community-Acquired Pneumonia by PCR in the Tyumen Region
title_short Results of Detecting SARS-CoV-2 and Other Pathogens of Community-Acquired Pneumonia by PCR in the Tyumen Region
title_sort results of detecting sars cov 2 and other pathogens of community acquired pneumonia by pcr in the tyumen region
topic pneumonia
pcr
sars-cov-2
co-infections
url https://journal.microbe.ru/jour/article/view/1375
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