Postoperative Infection after Anterior Cruciate Ligament Reconstruction: Prevention and Management

Infection following anterior cruciate ligament (ACL) reconstruction can be one of the most debilitating complications following ACL reconstruction. Its reported incidence is around 1%. Utilization of vancomycin for presoaking the graft is considered an established method for infection prevention. Th...

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Main Authors: George A. Komnos, George Chalatsis, Vasilios Mitrousias, Michael E. Hantes
Format: Article
Language:English
Published: MDPI AG 2022-11-01
Series:Microorganisms
Subjects:
Online Access:https://www.mdpi.com/2076-2607/10/12/2349
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author George A. Komnos
George Chalatsis
Vasilios Mitrousias
Michael E. Hantes
author_facet George A. Komnos
George Chalatsis
Vasilios Mitrousias
Michael E. Hantes
author_sort George A. Komnos
collection DOAJ
description Infection following anterior cruciate ligament (ACL) reconstruction can be one of the most debilitating complications following ACL reconstruction. Its reported incidence is around 1%. Utilization of vancomycin for presoaking the graft is considered an established method for infection prevention. The role of other agents, such as gentamycin needs further investigation. <i>Staphylococci</i> are the predominant causative pathogens, while particular attention should be paid to fungal infections due to their long-standing, occult process. Recent data demonstrate that hamstrings autograft may be at an elevated risk of being contaminated leading to subsequent septic arthritis. Diagnosis is set by clinical and laboratory findings and is usually confirmed by intraoperative cultures. Treatment varies, mainly depending on the intraoperative assessment. Satisfactory outcomes have been reported with both graft retaining and removal, and the decision is made upon the arthroscopic appearance of the graft and the characteristics of the infection. Of note, early management seems to lead to superior results, while persistent infection should be managed with graft removal in an attempt to protect the articular cartilage and the knee function.
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spelling doaj.art-1641c2d3fc904c6d9629485f6df68a702023-11-24T16:47:36ZengMDPI AGMicroorganisms2076-26072022-11-011012234910.3390/microorganisms10122349Postoperative Infection after Anterior Cruciate Ligament Reconstruction: Prevention and ManagementGeorge A. Komnos0George Chalatsis1Vasilios Mitrousias2Michael E. Hantes3The Department of Orthopaedic Surgery, Faculty of Medicine, School of Health Sciences, University of Hospital of Larissa, 41110 Larissa, GreeceThe Department of Orthopaedic Surgery, Faculty of Medicine, School of Health Sciences, University of Hospital of Larissa, 41110 Larissa, GreeceThe Department of Orthopaedic Surgery, Faculty of Medicine, School of Health Sciences, University of Hospital of Larissa, 41110 Larissa, GreeceThe Department of Orthopaedic Surgery, Faculty of Medicine, School of Health Sciences, University of Hospital of Larissa, 41110 Larissa, GreeceInfection following anterior cruciate ligament (ACL) reconstruction can be one of the most debilitating complications following ACL reconstruction. Its reported incidence is around 1%. Utilization of vancomycin for presoaking the graft is considered an established method for infection prevention. The role of other agents, such as gentamycin needs further investigation. <i>Staphylococci</i> are the predominant causative pathogens, while particular attention should be paid to fungal infections due to their long-standing, occult process. Recent data demonstrate that hamstrings autograft may be at an elevated risk of being contaminated leading to subsequent septic arthritis. Diagnosis is set by clinical and laboratory findings and is usually confirmed by intraoperative cultures. Treatment varies, mainly depending on the intraoperative assessment. Satisfactory outcomes have been reported with both graft retaining and removal, and the decision is made upon the arthroscopic appearance of the graft and the characteristics of the infection. Of note, early management seems to lead to superior results, while persistent infection should be managed with graft removal in an attempt to protect the articular cartilage and the knee function.https://www.mdpi.com/2076-2607/10/12/2349ACLseptic arthritisinfectionvancomycingraft removal
spellingShingle George A. Komnos
George Chalatsis
Vasilios Mitrousias
Michael E. Hantes
Postoperative Infection after Anterior Cruciate Ligament Reconstruction: Prevention and Management
Microorganisms
ACL
septic arthritis
infection
vancomycin
graft removal
title Postoperative Infection after Anterior Cruciate Ligament Reconstruction: Prevention and Management
title_full Postoperative Infection after Anterior Cruciate Ligament Reconstruction: Prevention and Management
title_fullStr Postoperative Infection after Anterior Cruciate Ligament Reconstruction: Prevention and Management
title_full_unstemmed Postoperative Infection after Anterior Cruciate Ligament Reconstruction: Prevention and Management
title_short Postoperative Infection after Anterior Cruciate Ligament Reconstruction: Prevention and Management
title_sort postoperative infection after anterior cruciate ligament reconstruction prevention and management
topic ACL
septic arthritis
infection
vancomycin
graft removal
url https://www.mdpi.com/2076-2607/10/12/2349
work_keys_str_mv AT georgeakomnos postoperativeinfectionafteranteriorcruciateligamentreconstructionpreventionandmanagement
AT georgechalatsis postoperativeinfectionafteranteriorcruciateligamentreconstructionpreventionandmanagement
AT vasiliosmitrousias postoperativeinfectionafteranteriorcruciateligamentreconstructionpreventionandmanagement
AT michaelehantes postoperativeinfectionafteranteriorcruciateligamentreconstructionpreventionandmanagement